Good Cosmetic Ingredient NOAEL Data

4-T-Butylcyclohexanol

INCI: 4-T-BUTYLCYCLOHEXANOL

CAS Number
98-52-2
Function
Fragrance ingredient / solvent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; no specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for 4-T-Butylcyclohexanol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 150 mg/kg bw/day oral rat oral REACH
NOAEL 150 mg/kg bw/day oral rat oral REACH
NOAEL 50 other oral rat oral REACH

Expert Verdict

4-T-Butylcyclohexanol is a fragrance ingredient prohibited in the EU but permitted in the US with no specific FDA restrictions.

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Concern Level: Low

Regulatory Flags

fragrance-component endocrine_disruptor ifra_fragrance

Frequently Asked Questions

Is 4-T-Butylcyclohexanol safe in cosmetics?

4-T-Butylcyclohexanol is a fragrance ingredient prohibited in the EU but permitted in the US with no specific FDA restrictions. The EU classifies 4-T-Butylcyclohexanol as "prohibited". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.

Is 4-T-Butylcyclohexanol allowed in the EU?

4-T-Butylcyclohexanol EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 4-T-Butylcyclohexanol do in cosmetics?

4-T-Butylcyclohexanol functions as: Fragrance ingredient / solvent. It is classified as a cosmetic ingredient in our database. CAS number: 98-52-2.

What is the Margin of Safety for 4-T-Butylcyclohexanol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for 4-T-Butylcyclohexanol?

The NOAEL (No Observed Adverse Effect Level) for 4-T-Butylcyclohexanol is 150 mg/kg bw/day based on a oral study via oral route in rat. A total of 3 study endpoints are available. Source: REACH.

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