Is 2,4-Diamino-5-methylphenetole HCl safe in cosmetics?
2,4-Diamino-5-methylphenetole HCl has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
2,4-Diamino-5-methylphenetole HCl
Also known as: UNII-8257131I5E, 1,3-Benzenediamine, 4-ethoxy-6-methyl-, dihydrochloride, 1,3-Benzenediamine, 4-ethoxy-6-methyl-, hydrochloride (1:2), 2,4-Diamino-5-ethoxytoluene dihydrochloride
INCI: 2,4-DIAMINO-5-METHYLPHENETOLE HCL
2,4-Diamino-5-methylphenetole HCl (CAS 113715-25-6) is a cosmetic cosmetic ingredient functioning as Hair dye (oxidative). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 113715-25-6 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
2,4-Diamino-5-methylphenetole HCl is prohibited in EU cosmetics but has active industrial GHS classifications (H317).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair dye (oxidative)
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
4-ethoxy-6-methylbenzene-1,3-diamine;dihydrochloride
InChIKey
YWJGJCGDAUWAQI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Not approved for use in hair dyes; no FDA authorization
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 2,4-Diamino-5-methylphenetole HCl.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1227
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for 2,4-Diamino-5-methylphenetole HCl.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
UNII-8257131I5E
1,3-Benzenediamine, 4-ethoxy-6-methyl-, dihydrochloride
1,3-Benzenediamine, 4-ethoxy-6-methyl-, hydrochloride (1:2)
2,4-Diamino-5-ethoxytoluene dihydrochloride
Chemical Function
Dye
Regulatory Lists
banned; Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 2,4-Diamino-5-methylphenetole HCl allowed in the EU?
2,4-Diamino-5-methylphenetole HCl EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does 2,4-Diamino-5-methylphenetole HCl do in cosmetics?
2,4-Diamino-5-methylphenetole HCl functions as: Hair dye (oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 113715-25-6.
Is 2,4-Diamino-5-methylphenetole HCl used outside cosmetics?
2,4-Diamino-5-methylphenetole HCl also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does 2,4-Diamino-5-methylphenetole HCl have different safety status in cosmetics vs industrial chemicals?
2,4-Diamino-5-methylphenetole HCl is prohibited in EU cosmetics but has active industrial GHS classifications (H317).
Compliance Tools
Check 2,4-Diamino-5-methylphenetole HCl compliance across multiple jurisdictions:
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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