4,5-Diamino-1-Methylpyrazole HCl

INCI: 4,5-DIAMINO-1-METHYLPYRAZOLE HCL

CAS Number
21616-59-1 (HCl salt)
Function
Hair dye (oxidative)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Coal tar hair dye exemption with labeling requirements

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Aromatic amine banned in EU; the 1-methyl derivative was prohibited while the 1-hydroxyethyl derivative was permitted under Annex III restrictions, indicating the methyl substitution pattern was deemed more hazardous or insufficiently supported.

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Concern Level: High

Frequently Asked Questions

Is 4,5-Diamino-1-Methylpyrazole HCl safe in cosmetics?

Aromatic amine banned in EU; the 1-methyl derivative was prohibited while the 1-hydroxyethyl derivative was permitted under Annex III restrictions, indicating the methyl substitution pattern was deemed more hazardous or insufficiently supported. The EU classifies 4,5-Diamino-1-Methylpyrazole HCl as "prohibited". Safety rating: POOR.

Is 4,5-Diamino-1-Methylpyrazole HCl allowed in the EU?

4,5-Diamino-1-Methylpyrazole HCl EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does 4,5-Diamino-1-Methylpyrazole HCl do in cosmetics?

4,5-Diamino-1-Methylpyrazole HCl functions as: Hair dye (oxidative). It is classified as a cosmetic ingredient in our database. CAS number: 21616-59-1 (HCl salt).

What is the Margin of Safety for 4,5-Diamino-1-Methylpyrazole HCl?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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