Is Allyl Alpha-Ionone safe in cosmetics?
Allyl Alpha-Ionone has a safety rating of "MODERATE" in our database. EU status: prohibited. US status: permitted.
Moderate
Cosmetic Ingredient
Allyl Alpha-Ionone
Also known as: 1,6-Heptadien-3-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-, 4-07-00-00833, Allyl cyclocitrylideneacetone, Allyl-alpha-ionone, BRN 3133731 (+10 more)
INCI: ALLYL ALPHA-IONONE
Allyl Alpha-Ionone (CAS 79-78-7) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient (fruity, ionone-type notes). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 79-78-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Allyl Alpha-Ionone is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H317).
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Fragrance ingredient (fruity, ionone-type notes)
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(1E)-1-(2,6,6-trimethylcyclohex-2-en-1-yl)hepta-1,6-dien-3-one
InChIKey
FXCYGAGBPZQRJE-ZHACJKMWSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Listed as a Substance Added to Food (GRAS for flavoring); permitted in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Allyl Alpha-Ionone.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
2 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 6480 | - | - |
| HRIPT | - | 0 | - | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (1)
JECFA Evaluation
ALLYL alpha-IONONE | 1998 | No safety concern at current levels of intake when used as a flavouring agent | TRS 891-JECFA 51/96 | FAS 42-JECFA 51/335
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Allyl Alpha-Ionone.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Known Synonyms
1,6-Heptadien-3-one, 1-(2,6,6-trimethyl-2-cyclohexen-1-yl)-
4-07-00-00833
Allyl cyclocitrylideneacetone
Allyl-alpha-ionone
BRN 3133731
Butenyl alpha-cyclocitrylidenemethyl ketone
Cetone V
Cyclocitrylidenemethyl butenyl ketone, alpha-
EINECS 201-225-9
FEMA No. 2033
Ionone, allyl alpha-
1-(2,6,6-Trimethyl-2-cyclohexen-1-yl)-1,6-heptadien-3-one
UNII-8IP66F9ODG
Allyl-α-ionone
Hexalon (fragrance)
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3184724
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
ALLYL ALPHA-IONONE
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is Allyl Alpha-Ionone allowed in the EU?
Allyl Alpha-Ionone EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Allyl Alpha-Ionone do in cosmetics?
Allyl Alpha-Ionone functions as: Fragrance ingredient (fruity, ionone-type notes). It is classified as a cosmetic ingredient in our database. CAS number: 79-78-7.
Is Allyl Alpha-Ionone used outside cosmetics?
Allyl Alpha-Ionone also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Allyl Alpha-Ionone have different safety status in cosmetics vs industrial chemicals?
Allyl Alpha-Ionone is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H317).
Compliance Tools
Check Allyl Alpha-Ionone compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent
Same category
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent
Same category
Fragrance (rich woody, orris/iris roo...
3,6-Dimethyl-3-Octyl Acetate
Excellent
Same category
Fragrance / Perfuming agent with flor...
3-Methyl-5-(2,2,3-Trimethyl-3-Cyclopentenyl)Pent-4-En-2-Ol (Sandalore)
Excellent
Same category
Perfuming / Fragrance (sandalwood note)
4-Tert-Butylcyclohexyl Acetate
Excellent
Same category
Fragrance
Acetoin
Excellent
Same category
Skin conditioning, fragrance
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
5-Methyl-Alpha-Ionone
Good
Chemical family
Fragrance (perfuming)
ACRYLAMIDE
Moderate
Chemical family
Not Reported
ACRYLIC ACID
Good
Chemical family
Nail Conditioning
Is Allyl Alpha-Ionone in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Allyl Alpha-Ionone in your formulation.