Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for CI 42090 (Brilliant Blue FCF). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 1000 mg/kg bw/day | oral | rat | Multigeneration Reproductive | COSMOS_DB |
| NOAEL | 2000 mg/kg bw/day | oral | rat | Reproductive-developmental | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | rat | Carcinogenicity | COSMOS_DB |
| NOAEL | 250 mg/kg bw/day | oral | mouse | Carcinogenicity | COSMOS_DB |
| NOAEL | 1500 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 200 mg/kg bw/day | oral | rabbit | Developmental | COSMOS_DB |
| NOAEL | 2500 mg/kg bw/day | oral | rat | Chronic | COSMOS_DB |
| NOAEL | 1000 mg/kg bw/day | oral | dog | Chronic | COSMOS_DB |
| NOAEL | 2000 mg/kg bw/day | oral | rat | Reproductive | COSMOS_DB |
Expert Verdict
One of the safest synthetic colorants with extensive safety record and extremely high margin of safety (>100).
Regulatory Flags
Frequently Asked Questions
Is CI 42090 (Brilliant Blue FCF) safe in cosmetics?
One of the safest synthetic colorants with extensive safety record and extremely high margin of safety (>100). The EU classifies CI 42090 (Brilliant Blue FCF) as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is CI 42090 (Brilliant Blue FCF) allowed in the EU?
CI 42090 (Brilliant Blue FCF) EU regulatory status: permitted. Maximum allowed concentration: 0.5% (hair dye use; no limit as general colorant under Annex IV Part 1). This is based on EU Regulation 1223/2009 and its amendments.
What does CI 42090 (Brilliant Blue FCF) do in cosmetics?
CI 42090 (Brilliant Blue FCF) functions as: Colorant, Hair Dyeing Agent. It is classified as a Colorant in our database. CAS number: 3844-45-9.
What is the Margin of Safety for CI 42090 (Brilliant Blue FCF)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for CI 42090 (Brilliant Blue FCF)?
The NOAEL (No Observed Adverse Effect Level) for CI 42090 (Brilliant Blue FCF) is 1000 mg/kg bw/day based on a Multigeneration Reproductive study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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