Moderate Cosmetic Ingredient NOAEL Data

CI 42090

CAS Number
3844-45-9
Function
Colorant, Hair Dyeing
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status Restricted
EU Max Conc. IV/63 (CI 42090) III/190 (Acid Blue 9; Acid Blue 9 Ammonium Salt; Acid Blue 9 Aluminum Lake)
🇺🇸 US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

10 study endpoints found for CI 42090. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral rat Multigeneration Reproductive COSMOS_DB
NOAEL 2000 mg/kg bw/day oral rat Reproductive-developmental COSMOS_DB
NOAEL 1000 mg/kg bw/day oral rat Chronic COSMOS_DB
NOAEL 1000 mg/kg bw/day oral rat Carcinogenicity COSMOS_DB
NOAEL 250 mg/kg bw/day oral mouse Carcinogenicity COSMOS_DB
NOAEL 1500 mg/kg bw/day oral rat Chronic COSMOS_DB
NOAEL 200 mg/kg bw/day oral rabbit Developmental COSMOS_DB
NOAEL 2500 mg/kg bw/day oral rat Chronic COSMOS_DB
NOAEL 1000 mg/kg bw/day oral dog Chronic COSMOS_DB
NOAEL 2000 mg/kg bw/day oral rat Reproductive COSMOS_DB

Expert Verdict

CI 42090 is listed in the EU CosIng database with functions: Colorant, Hair Dyeing It is restricted under EU Cosmetics Regulation. Restriction: IV/63 (CI 42090) III/190 (Acid Blue 9; Acid Blue 9 Ammonium Salt; Acid Blue 9 Aluminum Lake).

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Concern Level: Medium

Regulatory Flags

cosing-sourced eu-restricted needs-enrichment eu_children_restricted epa_safer_alternative ifra_fragrance fda_food_additive

Frequently Asked Questions

Is CI 42090 safe in cosmetics?

CI 42090 is listed in the EU CosIng database with functions: Colorant, Hair Dyeing It is restricted under EU Cosmetics Regulation. Restriction: IV/63 (CI 42090) III/190 (Acid Blue 9; Acid Blue 9 Ammonium Salt; Acid Blue 9 Aluminum Lake). The EU classifies CI 42090 as "Restricted". Safety rating: MODERATE. 10 toxicological study endpoint(s) are available in our database.

Is CI 42090 allowed in the EU?

CI 42090 EU regulatory status: Restricted. Maximum allowed concentration: IV/63 (CI 42090) III/190 (Acid Blue 9; Acid Blue 9 Ammonium Salt; Acid Blue 9 Aluminum Lake). This is based on EU Regulation 1223/2009 and its amendments.

What does CI 42090 do in cosmetics?

CI 42090 functions as: Colorant, Hair Dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 3844-45-9.

What is the NOAEL for CI 42090?

The NOAEL (No Observed Adverse Effect Level) for CI 42090 is 1000 mg/kg bw/day based on a Multigeneration Reproductive study via oral route in rat. A total of 10 study endpoints are available. Source: COSMOS_DB.

Compliance Tools

Check CI 42090 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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