Moderate Cosmetic Ingredient NOAEL Data

Acid Orange 7

INCI: CI 15510

CAS Number
633-96-5
Function
Cosmetic colorant; hair dye (semi-permanent)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not FDA-listed for cosmetic use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

1 study endpoint found for Acid Orange 7. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
LOAEL 2.5 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Azo dye that may metabolize to aromatic amines; further data requested for hair dye use above 1%

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Concern Level: Moderate

Regulatory Flags

colorant eu_children_restricted ifra_fragrance

Frequently Asked Questions

Is Acid Orange 7 safe in cosmetics?

Azo dye that may metabolize to aromatic amines; further data requested for hair dye use above 1% The EU classifies Acid Orange 7 as "permitted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.

Is Acid Orange 7 allowed in the EU?

Acid Orange 7 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Acid Orange 7 do in cosmetics?

Acid Orange 7 functions as: Cosmetic colorant; hair dye (semi-permanent). It is classified as a cosmetic ingredient in our database. CAS number: 633-96-5.

What is the Margin of Safety for Acid Orange 7?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Acid Orange 7?

The NOAEL (No Observed Adverse Effect Level) for Acid Orange 7 is 2.5 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.

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