Regulatory Status
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Safety Data
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Expert Verdict
GHS R36/37/38 applies to pure powder occupational handling only. No consumer-level concerns at cosmetic use concentrations. Fish-scale–derived guanine may present allergen labeling issues for fish-allergic consumers; voluntary disclosure recommended.
Regulatory Flags
Frequently Asked Questions
Is Guanine safe in cosmetics?
GHS R36/37/38 applies to pure powder occupational handling only. No consumer-level concerns at cosmetic use concentrations. Fish-scale–derived guanine may present allergen labeling issues for fish-allergic consumers; voluntary disclosure recommended. The EU classifies Guanine as "permitted". Safety rating: EXCELLENT.
Is Guanine allowed in the EU?
Guanine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Guanine do in cosmetics?
Guanine functions as: Opacifying agent; colorant (pearlescent/iridescent effect). It is classified as a cosmetic ingredient in our database. CAS number: 73-40-5.
What is the Margin of Safety for Guanine?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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