Regulatory Status
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Safety Data
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Expert Verdict
Adonis amurensis contains cardiac glycosides (cymarin, adonitoxin) that are pharmacologically active and potentially toxic. The entire genus Adonis is considered poisonous. Without rigorous characterization of glycoside content and dermal penetration data, topical use carries significant risk. Any safety assessment must quantify cardiac glycoside residuals.
Regulatory Flags
Frequently Asked Questions
Is Adonis Amurensis Extract safe in cosmetics?
Adonis amurensis contains cardiac glycosides (cymarin, adonitoxin) that are pharmacologically active and potentially toxic. The entire genus Adonis is considered poisonous. Without rigorous characterization of glycoside content and dermal penetration data, topical use carries significant risk. Any safety assessment must quantify cardiac glycoside residuals. The EU classifies Adonis Amurensis Extract as "permitted". Safety rating: POOR.
Is Adonis Amurensis Extract allowed in the EU?
Adonis Amurensis Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Adonis Amurensis Extract do in cosmetics?
Adonis Amurensis Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.
What is the Margin of Safety for Adonis Amurensis Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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