Aloe Barbadensis Leaf Juice
INCI: ALOE BARBADENSIS LEAF JUICE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Sensitization Profile
Contact sensitization data for Aloe Barbadensis Leaf Juice based on clinical patch test studies and IFRA standards.
Source: IVDK; ESSCA; NACDG
Expert Verdict
Aloe Barbadensis Leaf Juice (aloe vera) contains acemannan mucopolysaccharide as the primary wound-active constituent, exhibiting anti-inflammatory properties, moisturizing effects, and promotion of fibroblast activity. Purified forms are safe at cosmetic use levels; raw/unrefined aloe can contain anthraquinones (phototoxic and allergenic if >50 ppm). EU and US permit properly purified forms. Wound-healing claims may trigger drug classification in both regions.
Regulatory Flags
Frequently Asked Questions
Is Aloe Barbadensis Leaf Juice safe in cosmetics?
Aloe Barbadensis Leaf Juice (aloe vera) contains acemannan mucopolysaccharide as the primary wound-active constituent, exhibiting anti-inflammatory properties, moisturizing effects, and promotion of fibroblast activity. Purified forms are safe at cosmetic use levels; raw/unrefined aloe can contain anthraquinones (phototoxic and allergenic if >50 ppm). EU and US permit properly purified forms. Wound-healing claims may trigger drug classification in both regions. The EU classifies Aloe Barbadensis Leaf Juice as "permitted". Safety rating: GOOD.
Is Aloe Barbadensis Leaf Juice allowed in the EU?
Aloe Barbadensis Leaf Juice EU regulatory status: permitted. Maximum allowed concentration: No concentration limit for inner leaf gel/juice; whole-leaf extract requires specification controls (aloe-emodin anthraquinone avoidance). This is based on EU Regulation 1223/2009 and its amendments.
What does Aloe Barbadensis Leaf Juice do in cosmetics?
Aloe Barbadensis Leaf Juice functions as: Skin-conditioning, humectant, soothing, wound healing support. Acemannan (acetylated mannose polysaccharide) is the primary wound-active constituent: modulates macrophage activity, promotes fibroblast proliferation and ECM synthesis, reduces pro-inflammatory cytokines.. It is classified as a Active Ingredient in our database. CAS number: 85507-69-3.
What is the Margin of Safety for Aloe Barbadensis Leaf Juice?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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