Excellent Active Ingredient

Ascophyllum Nodosum Extract

INCI: ASCOPHYLLUM NODOSUM EXTRACT

CAS Number
84775-78-0
Function
Skin Brightening, Tyrosinase Inhibitor, Anti-melanogenesis, Anti-aging, Antioxidant, Skin Conditioning
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
EU Max Conc. 10%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; no specific FDA restriction; brightening claims supported by clinical evidence; MoCRA 2026 compliance required

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Clinically outstanding for skin brightening: combined with Crithmum maritimum, shown comparable efficacy to 4% hydroquinone + 0.05% tretinoin over 18 weeks in 56 women, inhibiting 13 of 14 melanin synthesis steps. This is a remarkable clinical benchmark for a natural ingredient. Pure skin brightening positioning backed by multi-step melanogenesis inhibition. Heavy metal COA required. Specify fucoidan/phlorotannin content in supplier specification for standardized brightening efficacy.

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Concern Level: Low

Regulatory Flags

heavy-metal-testing-required marine-origin skin-brightening-clinical-evidence hydroquinone-comparable-efficacy tyrosinase-inhibitor 13-of-14-melanin-steps wild-harvest-variability hyperpigmentation-indication eu_children_restricted

Frequently Asked Questions

Is Ascophyllum Nodosum Extract safe in cosmetics?

Clinically outstanding for skin brightening: combined with Crithmum maritimum, shown comparable efficacy to 4% hydroquinone + 0.05% tretinoin over 18 weeks in 56 women, inhibiting 13 of 14 melanin synthesis steps. This is a remarkable clinical benchmark for a natural ingredient. Pure skin brightening positioning backed by multi-step melanogenesis inhibition. Heavy metal COA required. Specify fucoidan/phlorotannin content in supplier specification for standardized brightening efficacy. The EU classifies Ascophyllum Nodosum Extract as "permitted". Safety rating: EXCELLENT.

Is Ascophyllum Nodosum Extract allowed in the EU?

Ascophyllum Nodosum Extract EU regulatory status: permitted. Maximum allowed concentration: 10%. This is based on EU Regulation 1223/2009 and its amendments.

What does Ascophyllum Nodosum Extract do in cosmetics?

Ascophyllum Nodosum Extract functions as: Skin Brightening, Tyrosinase Inhibitor, Anti-melanogenesis, Anti-aging, Antioxidant, Skin Conditioning. It is classified as a Active Ingredient in our database. CAS number: 84775-78-0.

What is the Margin of Safety for Ascophyllum Nodosum Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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