EXCELLENT Active Ingredient

Alpha-Glucan Oligosaccharide

INCI: ALPHA-GLUCAN OLIGOSACCHARIDE

Alpha-Glucan Oligosaccharide (CAS 27707-45-5) is a cosmetic active ingredient functioning as prebiotic, skin-conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.

View industrial chemical safety profile for CAS 27707-45-5 →

Function
prebiotic, skin-conditioning
Editorial assessment
EXCELLENT
Preliminary editorial note — not a computed safety verdict.

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted as cosmetic ingredient; safest microbiome category from FDA perspective with no live organism viability concerns; MoCRA 2026 compliance required

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Alpha-Glucan Oligosaccharide.

Calculate MoS for your specific formulation with the MoS Calculator.

Editorial summary

Preliminary editorial summary for Alpha-Glucan Oligosaccharide — not a computed safety verdict. See the sourced toxicological data above.

Regulatory Flags

prebiotic no-live-organisms competitive-exclusion synbiotic-combination-optimized quorum-sensing-inhibition antibiofilm microbiome-selectivity-critical microbiome-friendly selective-carbon-source

Frequently Asked Questions

Is Alpha-Glucan Oligosaccharide safe in cosmetics?

Alpha-Glucan Oligosaccharide has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Alpha-Glucan Oligosaccharide allowed in the EU?

Alpha-Glucan Oligosaccharide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Alpha-Glucan Oligosaccharide do in cosmetics?

Alpha-Glucan Oligosaccharide functions as: prebiotic, skin-conditioning. It is classified as a Active Ingredient in our database. CAS number: 27707-45-5.

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