Regulatory Status
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Safety Data
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Expert Verdict
Acetyl Tetrapeptide-5 has triple-mechanism clinical substantiation for periorbital puffiness and dark circles: ACE inhibition, reduced vascular permeability, and anti-glycation, with in-vivo studies confirming in-vitro findings and no safety concerns.
Frequently Asked Questions
Is Acetyl Tetrapeptide-5 safe in cosmetics?
Acetyl Tetrapeptide-5 has triple-mechanism clinical substantiation for periorbital puffiness and dark circles: ACE inhibition, reduced vascular permeability, and anti-glycation, with in-vivo studies confirming in-vitro findings and no safety concerns. The EU classifies Acetyl Tetrapeptide-5 as "permitted". Safety rating: EXCELLENT.
Is Acetyl Tetrapeptide-5 allowed in the EU?
Acetyl Tetrapeptide-5 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Acetyl Tetrapeptide-5 do in cosmetics?
Acetyl Tetrapeptide-5 functions as: Anti-edema peptide for periorbital area. Mechanism: ACE inhibition — dose-dependent inhibition of angiotensin-converting enzyme reduces microvascular pressure; reduced vascular permeability — decreases endothelial cell permeability, inhibiting interstitial fluid leakage; anti-glycation — protects collagen and SOD from fructose-mediated glycation, preserving elasticity. Strengthens capillary walls, reduces dark circle appearance.. It is classified as a Active Ingredient in our database. CAS number: Insufficient Data.
What is the Margin of Safety for Acetyl Tetrapeptide-5?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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