Good Active Ingredient Sensitization Data

Aloe Vera (Aloe Barbadensis Leaf Juice)

INCI: ALOE BARBADENSIS LEAF JUICE

CAS Number
85507-69-3
Function
Soothing / Humectant
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Aloe Vera (Aloe Barbadensis Leaf Juice) based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.5%
Cross-reactivity Group
none
Reaction Type
contact-dermatitis

Source: IVDK; ESSCA; NACDG

Expert Verdict

Aloe barbadensis leaf juice is a well-established skin conditioning and soothing agent generally recognized as safe for cosmetic use.

⚠️
Concern Level: Low

Regulatory Flags

epa_safer_alternative

Frequently Asked Questions

Is Aloe Vera (Aloe Barbadensis Leaf Juice) safe in cosmetics?

Aloe barbadensis leaf juice is a well-established skin conditioning and soothing agent generally recognized as safe for cosmetic use. The EU classifies Aloe Vera (Aloe Barbadensis Leaf Juice) as "permitted". Safety rating: GOOD.

Is Aloe Vera (Aloe Barbadensis Leaf Juice) allowed in the EU?

Aloe Vera (Aloe Barbadensis Leaf Juice) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Aloe Vera (Aloe Barbadensis Leaf Juice) do in cosmetics?

Aloe Vera (Aloe Barbadensis Leaf Juice) functions as: Soothing / Humectant. It is classified as a Active Ingredient in our database. CAS number: 85507-69-3.

What is the Margin of Safety for Aloe Vera (Aloe Barbadensis Leaf Juice)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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