Is Saccharide Isomerate safe in cosmetics?
Saccharide Isomerate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
UV Filter / Sunscreen
Saccharide Isomerate
Also known as: Pentavitin, UNII-W8K377W98I
INCI: SACCHARIDE ISOMERATE
Saccharide Isomerate (CAS 100843-69-4) is a cosmetic uv filter / sunscreen functioning as UV Filter. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 100843-69-4 →
Auto-generated CPSR Part A draft with source citations
Function
UV Filter
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not subject to FDA premarket approval for cosmetic use. CIR Expert Panel final report (September 2021) concluded safe in cosmetics in the present practices of use and concentration. Not classified as an OTC drug ingredient; no GRASE classification applies. Reported in 352 cosmetic products per 2021 VCRP data.
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Saccharide Isomerate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
7 property records from structured ingredient metadata.
acne
{"cas_number": "68937-71-7", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0-1", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restricti…
anti_aging
{"anti_aging_claim": "hydration-plumping", "mechanism_of_action": "Exfoliation, cell turnover acceleration, keratolytic", "target_skin_layer": "stratum corneum, epidermis", "collagen_stimulation": "Mild", "elastin_protection": "Mild", "wrinkle_reduction_pct": "6-12", "clinical_study_duration_weeks": "12", "sample_size": "40", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": …
cost_pricing
{"cost_tier": "premium", "estimated_cost_per_kg_usd_low": "85", "estimated_cost_per_kg_usd_high": "160", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "low", "primary_source_region": "Switzerland", "bulk_discount_threshold_kg": "10", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Hyaluronic …
hair_care
{"hair_function": "moisturizing", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "moisture", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "ker…
pregnancy_detail
{"pregnancy_safe": "yes", "breastfeeding_safe": "yes", "risk_category": "not-rated", "reason": "Safe; long-lasting moisturizer", "source": "dermatology literature"}
skin_suitability
{"oily_skin": "acceptable", "dry_skin": "recommended", "sensitive_skin": "recommended", "combination_skin": "acceptable", "normal_skin": "recommended", "acne_prone": "acceptable", "rosacea": "acceptable", "eczema": "acceptable", "hyperpigmentation": "acceptable", "aging_mature": "acceptable", "dehydrated": "recommended", "skin_benefit_primary": "hydrating", "skin_benefit_secondary": "skin-identica…
supply_chain
{"primary_producing_countries": "Switzerland, Germany, France", "secondary_producing_countries": "USA, Japan, China", "raw_material_origin": "synthetic", "agricultural_crop_or_wild_harvested": "enzymatic", "cultivation_climate_required": "biotech", "harvest_season": "continuous", "annual_global_production_tonnes": "420", "market_share_top_producer_pct": "68", "supply_chain_length": "complex", "lea…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Expert Verdict
Expert safety assessment and concern-level summary for Saccharide Isomerate.
Regulatory Flags
eu-unrestricted
cir-approved
non-sensitizing
no-sccs-opinion
Known Synonyms
Pentavitin
UNII-W8K377W98I
Chemical Function
Humectant
Regulatory Lists
Canada; pharmaceutical
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Saccharide Isomerate allowed in the EU?
Saccharide Isomerate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Saccharide Isomerate do in cosmetics?
Saccharide Isomerate functions as: UV Filter. It is classified as a UV Filter / Sunscreen in our database. CAS number: 100843-69-4.
Compliance Tools
Check Saccharide Isomerate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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SACCHAROMYCES BOULADARDII/(ASPARAGUS COCHINCHINENSIS/LYCIUM CHINENSE/OPHIOPOGON JAPONICUS/PANAX GINSENG/REHMANNIA GLUTINOSA) ROOT/PORIA COCOS FERMENT FILTRATE
Good
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Skin Conditioning
SACCHAROMYCES CEREVISIAE EXTRACT
Good
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Skin Conditioning
SACCHAROMYCES/(ACHYRANTHES BIDENTATA/ANGELICA GIGAS/ANGELICA PUBESCENS/ANGELICA TENUISSIMA/ASARUM SIEBOLDI/CNIDIUM OFFICINALE/LEDEBOURIELLA DIVARICATA/PAEONIA SUFFRUTICOSA) ROOT/EUCOMMIA ULMOIDES BARK/MAGNOLIA LILIFLORA BUD FERMENT FILTRATE
Good
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