Androstenedionyl Propionate

INCI: ANDROSTENEDIONYL PROPIONATE

CAS Number
Not assigned in CosIng
Function
Skin Conditioning – Humectant
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status restricted
US Notes No FDA pre-approval required for cosmetic ingredients; however, parent compound androstenedione (CAS 63-05-8) is a Schedule III anabolic steroid under US law

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Androstenedione is a direct precursor to testosterone and estrogen with potential endocrine-disrupting activity and likely problematic classification under MoCRA's adulterated provisions if hormonal effects are demonstrated; no CIR safety assessment exists.

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Concern Level: High

Frequently Asked Questions

Is Androstenedionyl Propionate safe in cosmetics?

Androstenedione is a direct precursor to testosterone and estrogen with potential endocrine-disrupting activity and likely problematic classification under MoCRA's adulterated provisions if hormonal effects are demonstrated; no CIR safety assessment exists. The EU classifies Androstenedionyl Propionate as "prohibited". Safety rating: POOR.

Is Androstenedionyl Propionate allowed in the EU?

Androstenedionyl Propionate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Androstenedionyl Propionate do in cosmetics?

Androstenedionyl Propionate functions as: Skin Conditioning – Humectant. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned in CosIng.

What is the Margin of Safety for Androstenedionyl Propionate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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