Regulatory Status
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Safety Data
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Expert Verdict
HIGH CONCERN - dietary supplements from A. muricata leaves showed "high degree of toxicity on Lund human mesencephalic cells" in vitro (Höllerhage et al., 2015); leaf infusions epidemiologically associated with atypical parkinsonism in Caribbean populations; leaves are a primary source of ACGs and alkaloids in the plant
Regulatory Flags
Frequently Asked Questions
Is Annona Muricata Leaf Extract safe in cosmetics?
HIGH CONCERN - dietary supplements from A. muricata leaves showed "high degree of toxicity on Lund human mesencephalic cells" in vitro (Höllerhage et al., 2015); leaf infusions epidemiologically associated with atypical parkinsonism in Caribbean populations; leaves are a primary source of ACGs and alkaloids in the plant The EU classifies Annona Muricata Leaf Extract as "permitted". Safety rating: POOR.
Is Annona Muricata Leaf Extract allowed in the EU?
Annona Muricata Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Annona Muricata Leaf Extract do in cosmetics?
Annona Muricata Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned in CosIng.
What is the Margin of Safety for Annona Muricata Leaf Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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