Annona Muricata Seedcake Powder

INCI: ANNONA MURICATA SEEDCAKE POWDER

CAS Number
Not assigned
Function
Likely exfoliant / skin conditioning (physical exfoliant from defatted seed residue)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restriction; manufacturer responsibility under MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

HIGHEST CONCERN among the 10 - Annonaceae seeds contain the highest concentration of acetogenins; even defatted seedcake may retain significant ACG residues; annonacin is lipophilic and a potent mitochondrial complex I inhibitor; A. squamosa seeds (closely related) confirmed as "source of environmental neurotoxins" with quantified squamocin (Bonneau et al., 2017); absolutely require ACG residual testing before use

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Concern Level: High

Frequently Asked Questions

Is Annona Muricata Seedcake Powder safe in cosmetics?

HIGHEST CONCERN among the 10 - Annonaceae seeds contain the highest concentration of acetogenins; even defatted seedcake may retain significant ACG residues; annonacin is lipophilic and a potent mitochondrial complex I inhibitor; A. squamosa seeds (closely related) confirmed as "source of environmental neurotoxins" with quantified squamocin (Bonneau et al., 2017); absolutely require ACG residual testing before use The EU classifies Annona Muricata Seedcake Powder as "permitted". Safety rating: POOR.

Is Annona Muricata Seedcake Powder allowed in the EU?

Annona Muricata Seedcake Powder EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Annona Muricata Seedcake Powder do in cosmetics?

Annona Muricata Seedcake Powder functions as: Likely exfoliant / skin conditioning (physical exfoliant from defatted seed residue). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Annona Muricata Seedcake Powder?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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