Regulatory Status
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Safety Data
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Expert Verdict
HIGHEST CONCERN among the 10 - Annonaceae seeds contain the highest concentration of acetogenins; even defatted seedcake may retain significant ACG residues; annonacin is lipophilic and a potent mitochondrial complex I inhibitor; A. squamosa seeds (closely related) confirmed as "source of environmental neurotoxins" with quantified squamocin (Bonneau et al., 2017); absolutely require ACG residual testing before use
Frequently Asked Questions
Is Annona Muricata Seedcake Powder safe in cosmetics?
HIGHEST CONCERN among the 10 - Annonaceae seeds contain the highest concentration of acetogenins; even defatted seedcake may retain significant ACG residues; annonacin is lipophilic and a potent mitochondrial complex I inhibitor; A. squamosa seeds (closely related) confirmed as "source of environmental neurotoxins" with quantified squamocin (Bonneau et al., 2017); absolutely require ACG residual testing before use The EU classifies Annona Muricata Seedcake Powder as "permitted". Safety rating: POOR.
Is Annona Muricata Seedcake Powder allowed in the EU?
Annona Muricata Seedcake Powder EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Annona Muricata Seedcake Powder do in cosmetics?
Annona Muricata Seedcake Powder functions as: Likely exfoliant / skin conditioning (physical exfoliant from defatted seed residue). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.
What is the Margin of Safety for Annona Muricata Seedcake Powder?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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