Good Active Ingredient Sensitization Data

Arctium Lappa Root Extract

INCI: ARCTIUM LAPPA ROOT EXTRACT

CAS Number
84012-13-5
Function
Skin conditioning, antioxidant, anti-inflammatory, hair conditioning, anti-dandruff
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No FDA restriction; no CIR monograph for root extract (seed oil reviewed separately, 2011); MoCRA product listing applies

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Arctium Lappa Root Extract based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
compositae-group
Reaction Type
contact-dermatitis

Source: IVDK; literature review

Expert Verdict

Well-regarded anti-inflammatory and antioxidant botanical (Burdock root) with EMA herbal assessment. Good tolerability profile at typical cosmetic concentrations. Asteraceae sensitization flag warrants CoA sesquiterpene lactone content data for leave-on products above 0.5%. No SCCS/CIR dossier โ€” full safety documentation burden on formulator. Request sesquiterpene lactone-mix content on supplier CoA.

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Concern Level: Low

Regulatory Flags

botanical data-gap no-cir-review asteraceae-cross-reactivity sensitizer-suspected

Frequently Asked Questions

Is Arctium Lappa Root Extract safe in cosmetics?

Well-regarded anti-inflammatory and antioxidant botanical (Burdock root) with EMA herbal assessment. Good tolerability profile at typical cosmetic concentrations. Asteraceae sensitization flag warrants CoA sesquiterpene lactone content data for leave-on products above 0.5%. No SCCS/CIR dossier โ€” full safety documentation burden on formulator. Request sesquiterpene lactone-mix content on supplier CoA. The EU classifies Arctium Lappa Root Extract as "permitted". Safety rating: GOOD.

Is Arctium Lappa Root Extract allowed in the EU?

Arctium Lappa Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Arctium Lappa Root Extract do in cosmetics?

Arctium Lappa Root Extract functions as: Skin conditioning, antioxidant, anti-inflammatory, hair conditioning, anti-dandruff. It is classified as a Active Ingredient in our database. CAS number: 84012-13-5.

What is the Margin of Safety for Arctium Lappa Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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