Bacillus Ferment

INCI: BACILLUS FERMENT

Bacillus Ferment is a cosmetic active ingredient functioning as Ferment derived from Bacillus species. Produces antimicrobial peptides. EU Regulation 1223/2009 status: permitted.

Auto-generated CPSR Part A draft with source citations
Function
Ferment derived from Bacillus species. Produces antimicrobial peptides (bacteriocins, iturin-class lipopeptides) and supports skin barrier function. Used as a multifunctional active in barrier-supporting and mild antimicrobial formulations.
Safety Rating
GOOD

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes Permitted in OTC cosmetics. Safety substantiation required. Endotoxin testing essential for gram-positive Bacillus ferments.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Bacillus Ferment.

Calculate MoS for your specific formulation with the MoS Calculator.

Additional Ingredient Properties

10 property records from structured ingredient metadata.

acne
{"anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "0", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-5", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_acne": "No restriction", "c…
anti_aging
{"anti_aging_claim": "cell-turnover, pore-minimizing", "mechanism_of_action": "Bioactive phytochemicals, antioxidant compounds", "target_skin_layer": "epidermis", "collagen_stimulation": "No", "elastin_protection": "No", "wrinkle_reduction_pct": "8-15", "clinical_study_duration_weeks": "8", "sample_size": "25", "double_blind": "Yes", "placebo_controlled": "Yes", "published_journal": "Phytotherapy …
anti_pollution
{"cas_number": "223749-120-5", "ingredient_class": "other", "primary_mechanism": "microbiome_protection", "pollution_types_targeted": "PM2_5", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "no", "NF_kB_inhib…
biopolymer
{"cas_number": "not_assigned", "polymer_class": "other", "botanical_source": "Bacillus sp. fermentation", "molecular_weight_range_kDa": "varies", "monosaccharide_composition": "polysaccharides with enzymes", "degree_of_branching": "varies", "charge_type": "anionic", "viscosity_1pct_solution_mPas": "5-50", "pseudoplastic_behavior": "weak", "thixotropy": "no", "yield_stress_Pa": "0", "gel_forming_ab…
cost_pricing
{"cost_tier": "premium", "estimated_cost_per_kg_usd_low": "95", "estimated_cost_per_kg_usd_high": "180", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "medium", "primary_source_region": "Korea/Japan", "bulk_discount_threshold_kg": "10", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Enzyme F…
deodorant
{"cas_number": "68332-21-8", "ingredient_class": "antimicrobial_deodorant", "mechanism_of_action": "bacterial_growth_inhibition", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "12-24", "odor_reduction_pct": "50-70", "bacteriostatic": "yes", "bactericidal": "yes", "target_bacteria": "selective", "microbiome_impact": "selective", "axillary_microbiome_effect": "varie…
depigmentation
{"cas_number": "formulation", "ingredient_class": "keratinocyte_turnover_enhancer", "primary_mechanism_of_action": "Fermentation metabolites provide gentle brightening and barrier support", "secondary_mechanisms": "Variable", "molecular_target": "other", "tyrosinase_inhibition_IC50_uM": "varies", "tyrosinase_inhibition_type": "competitive", "melanin_reduction_pct_in_vitro": "25-45", "melanin_reduc…
fermentation
{"cas_number": "proprietary", "ingredient_class": "fermentation_product", "production_organism": "Bacillus", "fermentation_type": "aerobic", "substrate_feedstock": "soybean, rice bran, glucose", "bioactive_compounds_produced": "enzymes, peptides, vitamins K2, surfactin", "mechanism_of_action_skin": "antimicrobial, antioxidant, enzyme activity", "skin_benefit_primary": "antimicrobial", "skin_benefi…

Expert Verdict

Expert safety assessment and concern-level summary for Bacillus Ferment.

Regulatory Flags

fermentation-derived antimicrobial-peptides barrier-support endotoxin-testing-required bacterial-origin

Frequently Asked Questions

Is Bacillus Ferment safe in cosmetics?

Bacillus Ferment has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.

Is Bacillus Ferment allowed in the EU?

Bacillus Ferment EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Bacillus Ferment do in cosmetics?

Bacillus Ferment functions as: Ferment derived from Bacillus species. Produces antimicrobial peptides (bacteriocins, iturin-class lipopeptides) and supports skin barrier function. Used as a multifunctional active in barrier-supporting and mild antimicrobial formulations.. It is classified as a Active Ingredient in our database.

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(ANGELICA KEISKEI/CHRYSANTHEMUM ZAWADSKII) LEAF/STEM/CINNAMOMUM CASSIA BARK/TRICHOSANTES KIRILOWII FRUIT/ULMUS DAVIDIANA BARK/ROOT/(PAEONIA JAPONICA/BUPLEURUM FALCATUM/POLYGALA TENUIFOLIA ROOT)/VISCUS ALBUM STEM EXTRACT
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BACILLUS
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Skin Conditioning
BACILLUS/(ASPARAGUS COCHINCHINENSIS/LYCIUM CHINENSE/OPHIOPOGON JAPONICUS/PANAX GINSENG/REHMANNIA GLUTINOSA) ROOT/PORIA COCOS FERMENT FILTRATE
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Skin Conditioning
BACILLUS/APRICOT SEED/ARTEMISIA ANNUA EXTRACT/PHASEOLUS ANGULARIS SEED/SOYBEAN SEED/WHEAT BRAN/XANTHIUM STRUMARIUM FRUIT EXTRACT FERMENT EXTRACT
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