Is Basic Blue 41 safe in cosmetics?
Basic Blue 41 has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
Basic Blue 41
Also known as: 2-[[4-[Ethyl(2-hydroxyethyl)amino]phenyl]azo]-6-methoxy-3-methylbenzothiazolium methyl sulfate, Benzothiazolium, 2-[2-[4-[ethyl(2-hydroxyethyl)amino]phenyl]diazenyl]-6-methoxy-3-methyl-, methyl sulfate (1:1), Benzothiazolium, 2-[[4-[ethyl(2-hydroxyethyl)amino]phenyl]azo]-6-methoxy-3-methyl-, methyl sulfate (salt), C.I. 11105, EC No.: 235-546-0 (+14 more)
INCI: BASIC BLUE 41
Basic Blue 41 (CAS 12270-13-2) is a cosmetic cosmetic ingredient functioning as Hair dyeing (cationic azo dye, benzothiazolium class). EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 12270-13-2 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Basic Blue 41 is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H314, H315, H318, H319, H335, H373, H400).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Hair dyeing (cationic azo dye, benzothiazolium class)
Safety Rating
POOR
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
Coal-tar hair dye exemption applies with required caution labeling
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Basic Blue 41.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1261
(EC) 2009/1223
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1261
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
Function Categories & List Membership
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Basic Blue 41.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
2-[[4-[Ethyl(2-hydroxyethyl)amino]phenyl]azo]-6-methoxy-3-methylbenzothiazolium methyl sulfate
Benzothiazolium, 2-[2-[4-[ethyl(2-hydroxyethyl)amino]phenyl]diazenyl]-6-methoxy-3-methyl-, methyl sulfate (1:1)
Benzothiazolium, 2-[[4-[ethyl(2-hydroxyethyl)amino]phenyl]azo]-6-methoxy-3-methyl-, methyl sulfate (salt)
C.I. 11105
EC No.: 235-546-0
EINECS 235-546-0
UNII-1ECX0J387P
Aizen Cathilon Blue GRLH
Anilan Blue GRL
Apollo Cationic Blue GRL
Astrazon Blue FGGL
BB 41
BB 41 (dye)
Basacryl Blue FD-X 3GL
Basacryl Blue X 3GL
Basic Blue X-GRRL
Blue X-GRL
Blue X-GRRL
Cationic Blue 41
Regulatory Lists
banned; Europe; Personal care
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
BASIC BLUE 41
ChEMBL ID
CHEMBL259143
Frequently Asked Questions
Is Basic Blue 41 allowed in the EU?
Basic Blue 41 EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Basic Blue 41 do in cosmetics?
Basic Blue 41 functions as: Hair dyeing (cationic azo dye, benzothiazolium class). It is classified as a cosmetic ingredient in our database. CAS number: 12270-13-2.
Is Basic Blue 41 used outside cosmetics?
Basic Blue 41 also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Basic Blue 41 have different safety status in cosmetics vs industrial chemicals?
Basic Blue 41 is prohibited in EU cosmetics but has active industrial GHS classifications (H302, H314, H315, H318, H319, H335, H373, H400).
Compliance Tools
Check Basic Blue 41 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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