Excellent Emollient

Borago Officinalis Seed Oil

INCI: BORAGO OFFICINALIS SEED OIL

CAS Number
84012-16-8
Function
Plant-derived emollient oil with approximately 20-24% GLA content plus high linoleic acid. Addresses delta-6-desaturase metabolic deficiency in atopic dermatitis at approximately double the GLA dose of evening primrose oil. Functions as emollient and skin-conditioning agent with anti-inflammatory and barrier-repair properties via omega-6 fatty acid metabolism.
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR Expert Panel assessed 244 plant-derived fatty acid oils as safe as used. Highest GLA content of common cosmetic oils (approximately 20-24%). Extreme PUFA content demands the most aggressive antioxidant protection protocol of all commonly used cosmetic oils.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR Expert Panel concluded plant-derived fatty acid oils, including borage oil, are safe as used. Highest GLA content of any common cosmetic oil (approximately 20-24%) โ€” approximately double that of evening primrose oil โ€” making it the premier GLA source for atopic dermatitis and barrier-compromised formulations where delta-6-desaturase deficiency is a target. Critical formulation caution: extreme PUFA content (LA + 20-24% GLA) makes this the highest peroxidation risk tier among common cosmetic oils; requires the most aggressive antioxidant protocol (high-dose tocopherol blend, rosemary CO2 extract), nitrogen blanketing, amber or opaque packaging, cold storage, and incoming peroxide value testing on every batch. Avoid blending with other high-PUFA oils without stability modeling.

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Concern Level: None

Regulatory Flags

cir-assessed high-pufa extreme-peroxidation-risk antioxidant-required cold-storage high-gla

Frequently Asked Questions

Is Borago Officinalis Seed Oil safe in cosmetics?

CIR Expert Panel concluded plant-derived fatty acid oils, including borage oil, are safe as used. Highest GLA content of any common cosmetic oil (approximately 20-24%) โ€” approximately double that of evening primrose oil โ€” making it the premier GLA source for atopic dermatitis and barrier-compromised formulations where delta-6-desaturase deficiency is a target. Critical formulation caution: extreme PUFA content (LA + 20-24% GLA) makes this the highest peroxidation risk tier among common cosmetic oils; requires the most aggressive antioxidant protocol (high-dose tocopherol blend, rosemary CO2 extract), nitrogen blanketing, amber or opaque packaging, cold storage, and incoming peroxide value testing on every batch. Avoid blending with other high-PUFA oils without stability modeling. The EU classifies Borago Officinalis Seed Oil as "permitted". Safety rating: EXCELLENT.

Is Borago Officinalis Seed Oil allowed in the EU?

Borago Officinalis Seed Oil EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Borago Officinalis Seed Oil do in cosmetics?

Borago Officinalis Seed Oil functions as: Plant-derived emollient oil with approximately 20-24% GLA content plus high linoleic acid. Addresses delta-6-desaturase metabolic deficiency in atopic dermatitis at approximately double the GLA dose of evening primrose oil. Functions as emollient and skin-conditioning agent with anti-inflammatory and barrier-repair properties via omega-6 fatty acid metabolism.. It is classified as a Emollient in our database. CAS number: 84012-16-8.

What is the Margin of Safety for Borago Officinalis Seed Oil?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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