Excellent Cosmetic Ingredient NOAEL Data

C12-15 Alkyl Ethylhexanoate

INCI: C12-15 ALKYL ETHYLHEXANOATE

CAS Number
90411-66-8
Function
Emollient, Skin Conditioning Agent
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Adequate โ€” CIR confirmed safe at reported concentrations up to 59%

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for C12-15 Alkyl Ethylhexanoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 300 mg/kg bw/day oral rat oral REACH
NOAEL 300 mg/kg bw/day oral - oral REACH

Expert Verdict

No significant safety concerns. CIR confirmed safe at concentrations up to 59%.

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Concern Level: Low

Frequently Asked Questions

Is C12-15 Alkyl Ethylhexanoate safe in cosmetics?

No significant safety concerns. CIR confirmed safe at concentrations up to 59%. The EU classifies C12-15 Alkyl Ethylhexanoate as "permitted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database.

Is C12-15 Alkyl Ethylhexanoate allowed in the EU?

C12-15 Alkyl Ethylhexanoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does C12-15 Alkyl Ethylhexanoate do in cosmetics?

C12-15 Alkyl Ethylhexanoate functions as: Emollient, Skin Conditioning Agent. It is classified as a cosmetic ingredient in our database. CAS number: 90411-66-8.

What is the Margin of Safety for C12-15 Alkyl Ethylhexanoate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for C12-15 Alkyl Ethylhexanoate?

The NOAEL (No Observed Adverse Effect Level) for C12-15 Alkyl Ethylhexanoate is 300 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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