Also known as: Methyl N,N,N-trimethyl-4-((4,7,7-trimethyl-3-oxobicyclo(2.2.1)hept-2-ylidene)methyl)anilinium sulphate, Benzenaminium, N,N,N-trimethyl-4-((4,7,7-trimethyl-3-oxobicyclo(2.2.1)hept-2-ylidene)methyl)-, methyl sulfate, EINECS 258-190-8
INCI: CAMPHOR BENZALKONIUM METHOSULFATE
Camphor Benzalkonium Methosulfate (CAS 52793-97-2) is a cosmetic cosmetic ingredient functioning as Antimicrobial, Antistatic, UV Absorber, UV Filter. NOAEL 60 mg/kg bw/day (PDF-verified against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: restricted, max 6%. Industrial safety data is also available in the chemical safety database.
US NotesBorderline margin of safety at 6%. Applicant requested reduction to 3% max to improve margin of safety.
For full compliance data across multiple jurisdictions, use the
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Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Camphor Benzalkonium Methosulfate.
Calculate MoS for your specific formulation with the
MoS Calculator.
Toxicological Studies
10 study endpoints found for Camphor Benzalkonium Methosulfate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
Endpoint
Value
Route
Species
Study Type
Source
NOAEL
=0.819 mg/kg
oral
rat
dermal absorption
SCCS_vision_codex
NOAEL
=0.819 mg/kg
oral
rat
dermal absorption
SCCS_vision_codex
NOAEL
=0.819 mg/kg
oral
rat
dermal absorption
SCCS_vision_codex
NOAEL
=0.819 mg/kg
oral
rat
dermal absorption
SCCS_vision_codex
NOAEL
=0.819 mg/kg
oral
rat
dermal absorption
SCCS_vision_codex
NOAEL
=0.819 mg/kg
oral
rat
dermal absorption
SCCS_vision_codex
NOAEL
=0.819 mg/kg
oral
rat
dermal absorption
SCCS_vision_codex
NOAEL
=0.819 mg/kg
oral
rat
dermal absorption
SCCS_vision_codex
NOAEL
=89.1 mg/kg bw
oral
rat
dermal absorption
SCCS_vision_codex
NOAEL
=89.1 mg/kg bw
oral
rat
dermal absorption
SCCS_vision_codex
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Camphor Benzalkonium Methosulfate across SCCS product categories, with measured dermal absorption where available.
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex VI — Permitted UV Filters
Max: 6%
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (VI - UV Filters)
Max: 0.06.
BRIN Brazil/India Cosmetics
India: Permitted UV Filter · max 0.06
Additional Jurisdictional Restrictions (3)
Jurisdiction
Status
Max %
Product Type
IN
permitted_uv_filter
6.0
sunscreen and other cosmetic products
BR
permitted_uv_filter
6
Sunscreen products
ASEAN
permitted_uv_filter
6%
-
Expanded Dermal Absorption Data
Cross-database dermal penetration: EPA Dryad physics-based, Roberts Mendeley permeation, and SCCS-aggregated measured values.
Aggregated DA Values (1 records across 5 sources)
Type
DA %
Method
Skin Model
SCCS Ref
measured_sccs_opinion
0.19%
-
-
SCCP/1202/08
Additional Ingredient Properties
2 property records from structured ingredient metadata.
Is Camphor Benzalkonium Methosulfate safe in cosmetics?
Camphor Benzalkonium Methosulfate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
Is Camphor Benzalkonium Methosulfate allowed in the EU?
Camphor Benzalkonium Methosulfate EU regulatory status: restricted. Maximum allowed concentration: 6%. This is based on EU Regulation 1223/2009 and its amendments.
What does Camphor Benzalkonium Methosulfate do in cosmetics?
Camphor Benzalkonium Methosulfate functions as: Antimicrobial, Antistatic, UV Absorber, UV Filter. It is classified as a cosmetic ingredient in our database. CAS number: 52793-97-2.
What is the NOAEL for Camphor Benzalkonium Methosulfate?
The NOAEL (No Observed Adverse Effect Level) for Camphor Benzalkonium Methosulfate is =0.819 mg/kg based on a dermal absorption study via oral route in rat. A total of 10 study endpoints are available. Source: SCCS_vision_codex.
Compliance Tools
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