Also known as: Methyl N,N,N-trimethyl-4-((4,7,7-trimethyl-3-oxobicyclo(2.2.1)hept-2-ylidene)methyl)anilinium sulphate, Benzenaminium, N,N,N-trimethyl-4-((4,7,7-trimethyl-3-oxobicyclo(2.2.1)hept-2-ylidene)methyl)-, methyl sulfate, EINECS 258-190-8
INCI: CAMPHOR BENZALKONIUM METHOSULFATE
Camphor Benzalkonium Methosulfate (CAS 52793-97-2) is a cosmetic cosmetic ingredient functioning as Antimicrobial, Antistatic, UV Absorber, UV Filter. Reported NOAEL =0.819 mg/kg in rat (SCCS Opinion); EU Regulation 1223/2009 status: restricted, max 6%. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 52793-97-2 →
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Margin of Safety, dermal absorption, and sensitization profile summaries for Camphor Benzalkonium Methosulfate.
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10 study endpoints found for Camphor Benzalkonium Methosulfate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =0.819 mg/kg | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.819 mg/kg | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.819 mg/kg | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.819 mg/kg | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.819 mg/kg | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.819 mg/kg | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.819 mg/kg | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =0.819 mg/kg | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =89.1 mg/kg bw | oral | rat | dermal absorption | SCCS Opinion |
| NOAEL | =89.1 mg/kg bw | oral | rat | dermal absorption | SCCS Opinion |
A margin-of-safety result previously shown for Camphor Benzalkonium Methosulfate has been withdrawn pending re-verification. We don't display safety verdicts we can't fully substantiate from the primary SCCS source — so this entry is being re-checked rather than shown unverified.
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| IN | permitted_uv_filter | 6.0 | sunscreen and other cosmetic products |
| BR | permitted_uv_filter | 6 | Sunscreen products |
| ASEAN | permitted_uv_filter | 6% | - |
Cross-database dermal penetration: EPA Dryad physics-based, Roberts Mendeley permeation, and SCCS-aggregated measured values.
| Type | DA % | Method | Skin Model | SCCS Ref |
|---|---|---|---|---|
| measured_sccs_opinion | 0.19% | - | - | SCCP/1202/08 |
Preliminary editorial summary for Camphor Benzalkonium Methosulfate — not a computed safety verdict. See the sourced toxicological data above.
Public NOAEL study rows linked to Camphor Benzalkonium Methosulfate by CAS number or substance name.
Units vary across source rows: mg/kg, mg/kg bw, mg/kg/day
| Absorption % | Method | Vehicle |
|---|---|---|
| 0.19% | SCCS opinion extraction | - |
Camphor Benzalkonium Methosulfate has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted. 10 toxicological study endpoint(s) are available in our database.
Camphor Benzalkonium Methosulfate EU regulatory status: restricted. Maximum allowed concentration: 6%. This is based on EU Regulation 1223/2009 and its amendments.
Camphor Benzalkonium Methosulfate functions as: Antimicrobial, Antistatic, UV Absorber, UV Filter. It is classified as a cosmetic ingredient in our database. CAS number: 52793-97-2.
The NOAEL (No Observed Adverse Effect Level) for Camphor Benzalkonium Methosulfate is =0.819 mg/kg based on a dermal absorption study via oral route in rat. A total of 10 study endpoints are available. Source: SCCS Opinion.
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