Excellent Cosmetic Ingredient NOAEL Data SCCS/CIR Reviewed

Guar Gum

Also known as: α-D-galacto-β-D-Mannan, α-D-Galactopyrano-β-D-mannopyranan, Burtonite V-7-E, EINECS 232-536-8, FEMA No. 2537 (+10 more)

INCI: GUAR GUM

Guar Gum (CAS 9000-30-0) is a cosmetic cosmetic ingredient functioning as rheology modifier, thickener, stabilizer. Reported NOAEL =1000 mg/kg body weight in rat (CIR_vision_codex); EU Regulation 1223/2009 status: permitted; 2 safety opinions reviewed (cir). Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.

View industrial chemical safety profile for CAS 9000-30-0 →

Auto-generated CPSR Part A draft with source citations
Function
rheology modifier, thickener, stabilizer
Safety Rating
EXCELLENT

Chemistry & Identifiers

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes GRAS for food; widely used in cosmetics and personal care. No restriction.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Guar Gum.

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

6 study endpoints found for Guar Gum. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL =1000 mg/kg body weight oral rat developmental toxicity CIR_vision_codex
NOAEL =1000 mg/kg body weight oral rat developmental toxicity CIR_vision_codex
NOAEL =1000 mg/kg body weight oral rat developmental toxicity CIR_vision_codex
NOAEL =1000 mg/kg body weight oral rat developmental toxicity CIR_vision_codex
NOAEL =2500 mg/kg bw/day - Rat chronic/long term toxicity EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx
NOAEL =2500 mg/kg bw/day - Rat chronic/long term toxicity EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx

Safety Opinions

Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).

cir
Verdict: safe
NOAEL: 1000 mg/kg body weight (oral)

netration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment. Keywords galactomannans, safety, cosmetics Introduction As given in the International Cosmetic Ingredient Dictio

cir
Verdict: safe
NOAEL: 1000 mg/kg body weight (not specified)

netration of these ingredients would be unlikely. The Panel concluded that these galactomannans are safe in the present practices of use and concentration described in this safety assessment. Keywords galactomannans, safety, cosmetics Introduction As given in the International Cosmetic Ingredient Dictio

EPA ToxValDB — Toxicity Values

3 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
LD50 =8100 mg/kg Mouse oral - ChemIDplus
LD50 =7000 mg/kg Rabbit oral - ChemIDplus
LD50 =6770 mg/kg Rat oral - ChemIDplus

Additional Ingredient Properties

10 property records from structured ingredient metadata.

anti_aging
{"anti_aging_claim": "hydration-plumping", "mechanism_of_action": "Humectant, water binding, barrier support", "target_skin_layer": "stratum corneum, epidermis", "collagen_stimulation": "No", "elastin_protection": "No", "wrinkle_reduction_pct": "4-8", "clinical_study_duration_weeks": "8", "sample_size": "30", "double_blind": "No", "placebo_controlled": "Yes", "published_journal": "JDD, Int J Cosme…
comedogenicity_detail
{"comedogenicity_rating": "0", "irritancy_rating": "0", "skin_type_suitability": "all,oily,combination,normal", "acne_safe": "yes", "source": "Natural thickener"}
cost_pricing
{"cost_tier": "budget", "estimated_cost_per_kg_usd_low": "8", "estimated_cost_per_kg_usd_high": "15", "natural_premium_markup_pct": "12", "organic_certified_premium_pct": "25", "supply_chain_volatility": "medium", "primary_source_region": "India/Pakistan", "synthetic_vs_natural_cost_ratio": "1.8", "bulk_discount_threshold_kg": "300", "seasonal_price_variation": "high", "commodity_or_specialty": "c…
deodorant
{"cas_number": "9000-30-0", "ingredient_class": "other", "mechanism_of_action": "other", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "0", "odor_reduction_pct": "0", "bacteriostatic": "no", "bactericidal": "no", "microbiome_impact": "neutral", "axillary_microbiome_effect": "varies by ingredient", "MIC_value_if_antimicrobial": "varies", "astringency_level": "varie…
emulsion_hlb
{"hlb_required_as_emulsifier": "no", "emulsifier_type": "o_w", "emulsion_stabilization_mechanism": "steric_stabilization", "co_emulsifier_pairs": "none_required", "optimal_oil_phase_pct": "3-15", "optimal_water_phase_pct": "85-97", "electrolyte_tolerance": "high", "pH_emulsion_stability_range": "3.0-10.5", "viscosity_building_contribution": "high", "droplet_size_range_um": "0.3-12", "zeta_potentia…
hair_care
{"hair_function": "styling", "hair_type_suitability": "all", "curl_pattern_suitability": "curly/coily", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "k…
ph_stability
{"optimal_ph_min": "4.0", "optimal_ph_max": "10.0", "stable_ph_min": "3.5", "stable_ph_max": "11.0", "degrades_above_ph": "12.0", "degrades_below_ph": "3.0", "ph_dependent_function": "Stable moderate pH range; salt sensitive", "formulation_note": "Degrades at pH extremes", "source": "Formulation literature"}
polymer
{"cas_number": "9000-30-0", "ingredient_class": "thickener", "polymer_type": "natural_polysaccharide", "chemical_backbone": "guar", "ionic_character": "nonionic", "viscosity_1pct_aqueous_mPas": "3000-5500", "pH_viscosity_sensitivity": "moderate", "salt_tolerance": "moderate", "electrolyte_effect_on_viscosity": "moderate", "temperature_viscosity_sensitivity": "moderate", "film_transparency": "trans…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Anti-caking agent Antioxidant Binder Deodorizer Drier Emulsifier Film former Flavouring and nutrient Fragrance Humectant
Regulatory List Membership (3)
EU Regulated in Personal Care EPA Safer Chemical Ingredients List (SCIL) FDA Substances Added to Food (EAFUS)

Expert Verdict

Expert safety assessment and concern-level summary for Guar Gum.

Regulatory Flags

eu-compliant biodegradable reach-spm-exempt natural-polymer cosmos-eligible ecocert gras acid-hydrolysis-risk synergistic-with-xanthan synergistic-with-locust-bean-gum epa_safer_alternative fda_food_additive jecfa_safe

NOAEL Studies Summary

View details ->

Public NOAEL study rows linked to Guar Gum by CAS number or substance name.

Studies
6
Lowest NOAEL
1000
Highest NOAEL
2500

Units vary across source rows: mg/kg bw/day, mg/kg body weight

EFSA_OpenFoodTox_EFSA_ReferencePoints.xlsx CIR_vision_codex

Known Synonyms

α-D-galacto-β-D-Mannan α-D-Galactopyrano-β-D-mannopyranan Burtonite V-7-E EINECS 232-536-8 FEMA No. 2537 Guar gum (Cyamopsis tetragonolobus (L.)) Jaguar A 20 B Jaguar gum A-20-D Jaguar No.124 Jaguar plus NCI-C50395 Supercol G.F. Cyamopsis tetragonoloba Guar Gum Seed Endosperm UNII-E89I1637KE

Chemical Function

Regulatory Lists

active_ingredient; Pesticides inert_ingredient; Pesticides inert_ingredient; non_food_use; Pesticides Europe; Personal care Europe; Personal care fracking SCIL (9/2019) Canada; pharmaceutical fracking; water food_additive; Substances Added to Food (formerly EAFUS) (2/2019)

Australian Status

AICIS status: listed

Cross-Vertical Safety Context

Same-CAS public records found in pharmaceutical data.

SOURCE ChEMBL / DrugCentral / FAERS DB_PHARMA count match

Pharmaceutical Data

Same-CAS rows from the pharmaceutical spoke database.

Adverse Event Associations
302
View full pharmaceutical profile →

Frequently Asked Questions

Is Guar Gum safe in cosmetics?

Guar Gum has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted. 6 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.

Is Guar Gum allowed in the EU?

Guar Gum EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Guar Gum do in cosmetics?

Guar Gum functions as: rheology modifier, thickener, stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 9000-30-0.

What is the NOAEL for Guar Gum?

The NOAEL (No Observed Adverse Effect Level) for Guar Gum is =1000 mg/kg body weight based on a developmental toxicity study via oral route in rat. A total of 6 study endpoints are available. Source: CIR_vision_codex.

Is Guar Gum used outside cosmetics?

Guar Gum also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

Is Guar Gum in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Guar Gum in your formulation.