Excellent Emollient Sensitization Data Dermal Penetration

Cetearyl Alcohol

Also known as: EINECS 267-008-6, UNII-2DMT128M1S

INCI: CETEARYL ALCOHOL

Cetearyl Alcohol (CAS 67762-27-0) is a cosmetic emollient functioning as Long-chain fatty alcohol (C16–C18 blend) functioning as emollient,. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.

View industrial chemical safety profile for CAS 67762-27-0 →

Auto-generated CPSR Part A draft with source citations
Function
Long-chain fatty alcohol (C16–C18 blend) functioning as emollient, co-emulsifier, and viscosity builder. Stabilizes O/W emulsions and improves skin feel.
Safety Rating
EXCELLENT

Chemistry & Identifiers

EC Number
267-008-6

Regulatory Status

EU EU Status permitted
US US Status permitted
US Notes CIR Expert Panel: safe at current use concentrations. Despite the word alcohol in the name, cetearyl alcohol is a long-chain fatty alcohol, not a drying solvent. Comedogenicity rating approximately 2 in REA; dilution-dependent caveat applies.

For full compliance data across multiple jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety, dermal absorption, and sensitization profile summaries for Cetearyl Alcohol.

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Cetearyl Alcohol based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.5%
Cross-reactivity Group
cetyl-group
Reaction Type
contact-dermatitis

Source: IVDK; ESSCA; NACDG

Dermal Penetration Profile

Skin absorption and penetration characteristics of Cetearyl Alcohol, relevant to systemic exposure and MoS calculations.

Absorption %
0.1-0.5%
Penetration Level
surface
Penetration Depth
surface only
Molecular Weight
270.5 Da
Log P
8.0
Systemic Absorption
no
Topical Bioavailability
0.05%
Safety Margin Factor
minimal

Source: CIR

EPA ToxValDB — Toxicity Values

4 toxicity values from EPA ToxValDB (aggregated from CCTE, HPV, ToxRefDB, IRIS, and other regulatory dossiers).

Endpoint Value Species Route Duration Source
LD50 >8000 mg/kg Rabbit dermal acute ECHA IUCLID
LD50 >8000 mg/kg Rabbit dermal acute ECHA IUCLID
LD50 >8000 mg/kg Rabbit dermal acute ECHA IUCLID
LD50 >8000 mg/kg Rabbit dermal acute ECHA IUCLID

ECHA REACH Registration

European Chemicals Agency REACH dossier and Substances of Very High Concern listing.

Registration Type
Full
Tonnage Band
10,000 - 100,000 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No

Typical Use Concentrations

Reported concentration ranges per product category from SCCS/CIR/industry sources.

Product Category Typical Range Max Reported Source
Face Cream 2–5 15 CIR/VCRP
Body Lotion 2–6 15 CIR/VCRP
Conditioner 3–6 15 CIR/VCRP

Additional Ingredient Properties

10 property records from structured ingredient metadata.

allergen_detail
{"eu_allergen_listed": "no", "allergen_class": "botanical", "cross_reactivity_group": "cetyl-group", "patch_test_frequency_pct": "0.5", "sensitization_rate": "low", "common_reaction_type": "contact-dermatitis", "ifra_restricted": "no", "source": "IVDK; ESSCA; NACDG"}
comedogenicity_detail
{"comedogenicity_rating": "2", "irritancy_rating": "0", "skin_type_suitability": "all,dry,combination,normal,mature", "acne_safe": "caution", "source": "Dermatology consensus"}
concentration
{"min_concentration_pct": "1.0", "max_concentration_pct": "10.0", "typical_concentration_pct": "5.0", "product_type": "Hair Conditioner", "function_at_concentration": "Conditioning, thickening", "source": "CIR Safety Assessment"}
deodorant
{"cas_number": "67762-27-0", "ingredient_class": "other", "mechanism_of_action": "other", "antiperspirant_efficacy_sweat_reduction_pct": "0", "deodorant_efficacy_hours": "0", "odor_reduction_pct": "0", "bacteriostatic": "no", "bactericidal": "no", "microbiome_impact": "neutral", "axillary_microbiome_effect": "varies by ingredient", "MIC_value_if_antimicrobial": "varies", "astringency_level": "vari…
dermal_absorption
{"molecular_weight_da": "270.5", "log_p_value": "8.0", "skin_penetration_level": "surface", "penetration_depth": "surface only", "absorption_pct": "0.1-0.5", "systemic_absorption": "no", "penetration_enhancer": "no", "occlusion_effect": "yes", "vehicle_dependent": "no", "skin_barrier_effect": "neutral", "bioavailability_topical_pct": "0.05", "safety_margin_factor": "minimal", "source": "CIR"}
emulsion_hlb
{"hlb_value": "15.5", "hlb_required_as_emulsifier": "no", "emulsifier_type": "o_w", "emulsion_stabilization_mechanism": "co_emulsifier_thickener", "co_emulsifier_pairs": "polysorbate_60,ceteareth_20", "optimal_oil_phase_pct": "15-40", "optimal_water_phase_pct": "60-85", "electrolyte_tolerance": "moderate", "pH_emulsion_stability_range": "4.0-9.5", "viscosity_building_contribution": "very_high", "z…
hair_care
{"hair_function": "conditioning", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "all", "protein_sensitivity": "neutral", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "yes", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "neutral", "ker…
hair_conditioning
{"cas_number": "67762-27-0", "ingredient_class": "fatty_alcohol", "chemical_type": "fatty_alcohol", "substantivity_to_hair": "good", "deposition_from_shampoo": "no", "deposition_from_conditioner": "yes", "conditioning_mechanism": "emollient_thickening", "hair_penetration": "surface_only", "molecular_weight_effect_on_penetration": "C16_C18_blend", "wet_combing_force_reduction_pct": "25-35", "dry_co…

Function Categories & List Membership

Cosmetic/Chemical Function Categories
Emulsifier Foamant Lubricating agent Opacifer Softener and conditioner Solvent Stabilizing agent Surfactant (surface active agent) Thickening agent Viscosity modifier
Regulatory List Membership (3)
EU Regulated in Personal Care EU Restricted for Children (Cosmetics) FDA Indirect Food Contact Additives

Expert Verdict

Expert safety assessment and concern-level summary for Cetearyl Alcohol.

Regulatory Flags

eu_children_restricted

Known Synonyms

EINECS 267-008-6 UNII-2DMT128M1S

Chemical Function

Softener and conditioner Emulsifier Stabilizing agent

Regulatory Lists

inert_ingredient; non_food_use; Pesticides Europe; Personal care children; Europe; Personal care children; Europe; Personal care children; Europe; Personal care - general moisturizing - hand/body lotion children; Europe; Personal care Europe; Personal care - liniment Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care Europe; Personal care CEDI Indirect additives food contact (10/2018) active_ingredient; animal_products; Europe; pharmaceutical; residue

Australian Status

AICIS status: listed

Frequently Asked Questions

Is Cetearyl Alcohol safe in cosmetics?

Cetearyl Alcohol has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.

Is Cetearyl Alcohol allowed in the EU?

Cetearyl Alcohol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cetearyl Alcohol do in cosmetics?

Cetearyl Alcohol functions as: Long-chain fatty alcohol (C16–C18 blend) functioning as emollient, co-emulsifier, and viscosity builder. Stabilizes O/W emulsions and improves skin feel.. It is classified as a Emollient in our database. CAS number: 67762-27-0.

Is Cetearyl Alcohol used outside cosmetics?

Cetearyl Alcohol also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.

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