Excellent Emollient Sensitization Data Dermal Penetration

Cetearyl Alcohol

INCI: CETEARYL ALCOHOL

CAS Number
67762-27-0
Function
Long-chain fatty alcohol (C16–C18 blend) functioning as emollient, co-emulsifier, and viscosity builder. Stabilizes O/W emulsions and improves skin feel.
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR Expert Panel: safe at current use concentrations. Despite the word alcohol in the name, cetearyl alcohol is a long-chain fatty alcohol, not a drying solvent. Comedogenicity rating approximately 2 in REA; dilution-dependent caveat applies.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Cetearyl Alcohol based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
botanical
EU Allergen Listed
no
Patch Test Positive Rate
0.5%
Cross-reactivity Group
cetyl-group
Reaction Type
contact-dermatitis

Source: IVDK; ESSCA; NACDG

Dermal Penetration Profile

Skin absorption and penetration characteristics of Cetearyl Alcohol, relevant to systemic exposure and MoS calculations.

Absorption %
0.1-0.5%
Penetration Level
surface
Penetration Depth
surface only
Molecular Weight
270.5 Da
Log P
8.0
Systemic Absorption
no
Topical Bioavailability
0.05%
Safety Margin Factor
minimal

Source: CIR

Expert Verdict

Well-established, safe fatty alcohol with dual emollient and co-emulsifier function. Low comedogenicity concern at finished-product concentrations. Suitable for sensitive skin. The alcohol nomenclature is misleading; cetearyl alcohol does not exhibit drying or irritating properties of short-chain alcohols. Widely used, well-tolerated ingredient.

⚠️
Concern Level: None

Regulatory Flags

eu_children_restricted

Frequently Asked Questions

Is Cetearyl Alcohol safe in cosmetics?

Well-established, safe fatty alcohol with dual emollient and co-emulsifier function. Low comedogenicity concern at finished-product concentrations. Suitable for sensitive skin. The alcohol nomenclature is misleading; cetearyl alcohol does not exhibit drying or irritating properties of short-chain alcohols. Widely used, well-tolerated ingredient. The EU classifies Cetearyl Alcohol as "permitted". Safety rating: EXCELLENT.

Is Cetearyl Alcohol allowed in the EU?

Cetearyl Alcohol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cetearyl Alcohol do in cosmetics?

Cetearyl Alcohol functions as: Long-chain fatty alcohol (C16–C18 blend) functioning as emollient, co-emulsifier, and viscosity builder. Stabilizes O/W emulsions and improves skin feel.. It is classified as a Emollient in our database. CAS number: 67762-27-0.

What is the Margin of Safety for Cetearyl Alcohol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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