Regulatory Status
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Safety Data
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Expert Verdict
CRITICAL: GHS Acute Tox. 3 oral; harmful via dermal and inhalation routes; cytotoxic and potentially genotoxic; no established safe use level in cosmetics; would require robust toxicological dossier for CPSR
Frequently Asked Questions
Is Chelidonine safe in cosmetics?
CRITICAL: GHS Acute Tox. 3 oral; harmful via dermal and inhalation routes; cytotoxic and potentially genotoxic; no established safe use level in cosmetics; would require robust toxicological dossier for CPSR The EU classifies Chelidonine as "prohibited". Safety rating: POOR.
Is Chelidonine allowed in the EU?
Chelidonine EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Chelidonine do in cosmetics?
Chelidonine functions as: Skin conditioning agent (isolated alkaloid from Chelidonium majus). It is classified as a cosmetic ingredient in our database. CAS number: 476-32-4.
What is the Margin of Safety for Chelidonine?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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