Cholesteryl Acetate

INCI: CHOLESTERYL ACETATE

CAS Number
604-35-3
Function
Skin conditioning agent (emollient, cholesterol ester for barrier repair)
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR reviewed cholesterol and derivatives โ€” concluded safe as used (1986, reaffirmed 2004 and 2024)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Animal-derived ingredient with potential for infectious agents (prions), heavy metals, and pesticide residues; biologically-derived impurities (nucleic acids, proteins, endotoxins) must be controlled.

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Concern Level: Low

Frequently Asked Questions

Is Cholesteryl Acetate safe in cosmetics?

Animal-derived ingredient with potential for infectious agents (prions), heavy metals, and pesticide residues; biologically-derived impurities (nucleic acids, proteins, endotoxins) must be controlled. The EU classifies Cholesteryl Acetate as "permitted". Safety rating: EXCELLENT.

Is Cholesteryl Acetate allowed in the EU?

Cholesteryl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cholesteryl Acetate do in cosmetics?

Cholesteryl Acetate functions as: Skin conditioning agent (emollient, cholesterol ester for barrier repair). It is classified as a cosmetic ingredient in our database. CAS number: 604-35-3.

What is the Margin of Safety for Cholesteryl Acetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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