Is Cholesteryl Butyrate safe in cosmetics?
Cholesteryl Butyrate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Cholesteryl Butyrate
INCI: CHOLESTERYL BUTYRATE
Cholesteryl Butyrate (CAS 521-13-1) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent (emollient/lipid). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 521-13-1 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent (emollient/lipid)
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
[(3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] butanoate
InChIKey
CKDZWMVGDHGMFR-GTPODGLVSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR reviewed within the cholesterol family — safe as used
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Cholesteryl Butyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Cholesteryl Butyrate.
Chemical Function
Softener and conditioner
Frequently Asked Questions
Is Cholesteryl Butyrate allowed in the EU?
Cholesteryl Butyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Cholesteryl Butyrate do in cosmetics?
Cholesteryl Butyrate functions as: Skin conditioning agent (emollient/lipid). It is classified as a cosmetic ingredient in our database. CAS number: 521-13-1.
Compliance Tools
Check Cholesteryl Butyrate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
Acacia Decurrens/Jojoba/Sunflower Seed Wax Polyglyceryl-3 Esters
Excellent
Same category
Skin conditioning emollient, texturizer
Acetic/Linoleic/Palmitic Triglyceride
Excellent
Same category
Skin conditioning (emollient)
Acetyl Ornithine
Excellent
Same category
Emollient
Acetyl Proline
Excellent
Same category
Emollient
Acetyl Triethylhexyl Citrate
Excellent
Same category
Emollient, Film Forming, Plasticiser
Acetyl Trihexyl Citrate
Excellent
Same category
Plasticiser, Skin Conditioning (Emoll...
1-Methylhydantoin-2-imide (Creatinine)
Excellent
Similar safety
Skin conditioning (skin brightening/l...
2,6-Dimethyl-7-octen-2-ol (Dihydromyrcenol)
Excellent
Similar safety
Fragrance (perfuming), masking
2-Ethoxy-2,6,6-Trimethyl-9-Methylenebicyclo[3.3.1]Nonane (Boisiris™)
Excellent
Similar safety
Fragrance (rich woody, orris/iris roo...
2-Hydroxypropylcarbamato Amodimethicone
Excellent
Similar safety
Hair conditioning; modified aminosili...
2-O-Ethyl Ascorbic Acid
Excellent
Similar safety
Softener and conditioner
3 O Ethyl Ascorbic Acid
Excellent
Similar safety
Antioxidant; tyrosinase inhibitor; me...
MORINDA OFFICINALIS ROOT EXTRACT
Good
Chemical family
Antioxidant, Skin Conditioning
CHOLECALCIFEROL
Poor
Browse nearby
Skin-conditioning agent; vitamin D re...
CHRYSANTHEMUM INDICUM FLOWER EXTRACT
Good
Browse nearby
Skin Conditioning
Is Cholesteryl Butyrate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Cholesteryl Butyrate in your formulation.