Is CI 20470 safe in cosmetics?
CI 20470 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: restricted. 10 toxicological study endpoint(s) are available in our database.
CI 20470
Also known as: Naphthol Blue Black, C.I. Acid Black 1, 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-3-[2-(4-nitrophenyl)diazenyl]-6-(2-phenyldiazenyl)-, sodium salt (1:2), D and C Black No. 1, D And C Black Number 1 (+15 more)
CI 20470 (CAS 1064-48-8) is a cosmetic cosmetic ingredient functioning as Colorant. NOAEL 0.78 mg/kg bw/day (PDF-verified against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 1064-48-8 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
CI 20470 is classified GHS Danger (H315, H317, H319, H335, H372) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Colorant
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
disodium;4-amino-5-hydroxy-3-[(4-nitrophenyl)diazenyl]-6-phenyldiazenylnaphthalene-2,7-disulfonate
InChIKey
AOMZHDJXSYHPKS-UHFFFAOYSA-L
Regulatory Status
EU EU Status
permitted
US US Status
restricted
US Notes
Not listed as FDA-approved color additive for cosmetics; not in 21 CFR Part 74 or 82; use restricted in US
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for CI 20470.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for CI 20470. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =0.78 mg/kg bw/d | oral | rat | dermal absorption | SCCS_vision_codex |
| NOAEL | =0.78 mg/kg bw/d | oral | rat | dermal absorption | SCCS_vision_codex |
| NOAEL | =0.78 mg/kg bw/d | oral | rat | dermal absorption | SCCS_vision_codex |
| NOAEL | =0.78 mg/kg bw/d | oral | rat | dermal absorption | SCCS_vision_codex |
| NOAEL | =5 mg/kg/day | - | - | NOAEL study | SCCS_vision_codex |
| NOAEL | =5 mg/kg/day | - | - | NOAEL study | SCCS_vision_codex |
| NOAEL | =5 mg/kg/day | - | - | NOAEL study | SCCS_vision_codex |
| NOAEL | =5 mg/kg/day | - | - | NOAEL study | SCCS_vision_codex |
| NOAEL | =40 mg/kg bw/day | - | human | developmental toxicity | SCCS_vision_codex |
| NOAEL | =40 mg/kg bw/day | - | human | developmental toxicity | SCCS_vision_codex |
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for CI 20470 across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex IV — Permitted Colorants
Product type: Black
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
Product type: Hair dye substance in non-oxidative hair dye products. Max: 0,5 %.
BRIN Brazil/India Cosmetics
India: Restricted · max 0,5 %
India: Permitted Colorant
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| ASEAN | permitted_colorant | - | Not eye area |
Expanded Dermal Absorption Data
Cross-database dermal penetration: EPA Dryad physics-based, Roberts Mendeley permeation, and SCCS-aggregated measured values.
Aggregated DA Values (5 records across 5 sources)
| Type | DA % | Method | Skin Model | SCCS Ref |
|---|---|---|---|---|
| measured | 1.0% | - | - | SCCS/0148 |
| measured | 0.5% | in_vitro | - | SCCS/0148 |
| measured | 0.03% | - | - | SCCS/0148 |
| measured | 0.6% | - | - | SCCS/0148 |
| measured | 3.3% | - | - | SCCS/0148 |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Dye
Regulatory List Membership (2)
EU Regulated in Personal Care
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for CI 20470.
Regulatory Flags
azo-dye
rinse-off-only
eu-annex-iv
not-fda-approved
aromatic-amine-concern
eu_cosing_listed
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to CI 20470 by CAS number or substance name.
Studies
12
Lowest NOAEL
0.78
Highest NOAEL
40
Units vary across source rows: mg/kg/day, mg/kg bw/day, mg/kg bw/d
SCCS_vision_codex
Dermal Absorption
View details ->| Absorption % | Method | Vehicle |
|---|---|---|
| 1.0% | - | - |
| 0.5% | in_vitro | - |
| 0.03% | - | - |
| 0.6% | - | - |
| 3.3% | - | - |
Known Synonyms
Naphthol Blue Black
C.I. Acid Black 1
2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-3-[2-(4-nitrophenyl)diazenyl]-6-(2-phenyldiazenyl)-, sodium salt (1:2)
D and C Black No. 1
D And C Black Number 1
D&C Black 1
Acid Black H
Acid Black 1
Acid Black 10A
Acid Black 10B
Acid Black 10BA
Acid Black 10BN
Acid Black 12B
Acid Black 4BN
Acid Black 4BNU
Acid Black Base M
Acid Black BRX
Acid Black BX
Acid Black JVS
Acid Blue Black
Chemical Function
Dye
Regulatory Lists
Europe; Personal care; restricted
Europe; Personal care - hair coloring
Europe; Personal care - hair coloring
Europe; Personal care - hair coloring
inert_ingredient; non_food_use; Pesticides
Europe; Personal care
Australian Status
AICIS status: listed
Frequently Asked Questions
Is CI 20470 allowed in the EU?
CI 20470 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does CI 20470 do in cosmetics?
CI 20470 functions as: Colorant. It is classified as a cosmetic ingredient in our database. CAS number: 1064-48-8.
What is the NOAEL for CI 20470?
The NOAEL (No Observed Adverse Effect Level) for CI 20470 is =0.78 mg/kg bw/d based on a dermal absorption study via oral route in rat. A total of 10 study endpoints are available. Source: SCCS_vision_codex.
Is CI 20470 used outside cosmetics?
CI 20470 also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does CI 20470 have different safety status in cosmetics vs industrial chemicals?
CI 20470 is classified GHS Danger (H315, H317, H319, H335, H372) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check CI 20470 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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