Citraconic Anhydride

CAS Number
616-02-4
Function
No specific technical function
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No CIR review; not commonly used as a finished cosmetic ingredient; TSCA listed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Corrosive and acutely toxic dermally with respiratory and skin sensitization hazards; causes severe burns and not recommended for leave-on or rinse-off cosmetic products without complete reaction/neutralization.

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Citraconic Anhydride safe in cosmetics?

Corrosive and acutely toxic dermally with respiratory and skin sensitization hazards; causes severe burns and not recommended for leave-on or rinse-off cosmetic products without complete reaction/neutralization. The EU classifies Citraconic Anhydride as "prohibited". Safety rating: POOR.

Is Citraconic Anhydride allowed in the EU?

Citraconic Anhydride EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Citraconic Anhydride do in cosmetics?

Citraconic Anhydride functions as: No specific technical function. It is classified as a cosmetic ingredient in our database. CAS number: 616-02-4.

What is the Margin of Safety for Citraconic Anhydride?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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