Excellent Cosmetic Ingredient NOAEL Data

Collagen Powder

INCI: COLLAGEN

CAS Number
9007-34-5
Function
Hair conditioning, skin conditioning, humectant, film forming
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes FDA permitted; same regulations as Collagen above. Compliant with 21 CFR 700.27

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Collagen Powder. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 10000 mg/kg bw/day oral rat Subchronic COSMOS_DB
NOAEL 10000 mg/kg bw/day oral rat Subchronic COSMOS_DB

Expert Verdict

Collagen powder is permitted for cosmetic use with negligible absorption and low sensitization; inhalation exposure from powder cosmetics is 400-1000 fold below workplace limits for inert respirable particles. BSE and fish-allergen considerations apply.

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Concern Level: Low

Regulatory Flags

potential-allergen fda_food_additive

Frequently Asked Questions

Is Collagen Powder safe in cosmetics?

Collagen powder is permitted for cosmetic use with negligible absorption and low sensitization; inhalation exposure from powder cosmetics is 400-1000 fold below workplace limits for inert respirable particles. BSE and fish-allergen considerations apply. The EU classifies Collagen Powder as "permitted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database.

Is Collagen Powder allowed in the EU?

Collagen Powder EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Collagen Powder do in cosmetics?

Collagen Powder functions as: Hair conditioning, skin conditioning, humectant, film forming. It is classified as a cosmetic ingredient in our database. CAS number: 9007-34-5.

What is the Margin of Safety for Collagen Powder?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Collagen Powder?

The NOAEL (No Observed Adverse Effect Level) for Collagen Powder is 10000 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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