Poor Cosmetic Ingredient

Colloidal Palladium

INCI: COLLOIDAL PALLADIUM

CAS Number
7440-05-3 (Palladium)
Function
Colorant, skin conditioning
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes FDA: No specific cosmetic restrictions. Listed on TSCA. Palladium chloride LD50 oral (rat) = 200 mg/kg indicates moderate acute toxicity. General cosmetic safety requirements apply.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL SENSITIZER. Palladium has one of the highest metal sensitization rates after nickel. Cross-reactivity with nickel means any nickel-sensitized individual (~15% of women) is at elevated risk. No adequate cosmetic safety assessment exists. Palladium compounds classified hazardous (H228, H315, H317, H319, H335). Recommend against use without comprehensive toxicology package.

⚠️
Concern Level: High

Regulatory Flags

potential-allergen colorant

Frequently Asked Questions

Is Colloidal Palladium safe in cosmetics?

CRITICAL SENSITIZER. Palladium has one of the highest metal sensitization rates after nickel. Cross-reactivity with nickel means any nickel-sensitized individual (~15% of women) is at elevated risk. No adequate cosmetic safety assessment exists. Palladium compounds classified hazardous (H228, H315, H317, H319, H335). Recommend against use without comprehensive toxicology package. The EU classifies Colloidal Palladium as "prohibited". Safety rating: POOR.

Is Colloidal Palladium allowed in the EU?

Colloidal Palladium EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Colloidal Palladium do in cosmetics?

Colloidal Palladium functions as: Colorant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 7440-05-3 (Palladium).

What is the Margin of Safety for Colloidal Palladium?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Colloidal Palladium compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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