Conobea Scoparioides Leaf Oil

INCI: CONOBEA SCOPARIOIDES LEAF OIL

CAS Number
950903-91-0
Function
Fragrance (perfuming)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated by FDA. No CIR review. Permitted as a fragrance ingredient under general provisions.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL: High cytotoxicity demonstrated in vitro and in vivo anti-tumor activity (55.8% tumor mass inhibition at 80 mg/kg in mice). Contains thymol (known sensitizer/irritant) and ฮฑ-phellandrene (flagged as potential carcinogen in silico). Not recommended for cosmetic use without comprehensive toxicological assessment including RIFM evaluation, dermal sensitization (DPRA/KeratinoSens), genotoxicity, and repeat-dose toxicity studies. IFRA status unclear for this specific species.

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Concern Level: High

Regulatory Flags

plant-oil potential-allergen fragrance-component

Frequently Asked Questions

Is Conobea Scoparioides Leaf Oil safe in cosmetics?

CRITICAL: High cytotoxicity demonstrated in vitro and in vivo anti-tumor activity (55.8% tumor mass inhibition at 80 mg/kg in mice). Contains thymol (known sensitizer/irritant) and ฮฑ-phellandrene (flagged as potential carcinogen in silico). Not recommended for cosmetic use without comprehensive toxicological assessment including RIFM evaluation, dermal sensitization (DPRA/KeratinoSens), genotoxicity, and repeat-dose toxicity studies. IFRA status unclear for this specific species. The EU classifies Conobea Scoparioides Leaf Oil as "prohibited". Safety rating: POOR.

Is Conobea Scoparioides Leaf Oil allowed in the EU?

Conobea Scoparioides Leaf Oil EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Conobea Scoparioides Leaf Oil do in cosmetics?

Conobea Scoparioides Leaf Oil functions as: Fragrance (perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 950903-91-0.

What is the Margin of Safety for Conobea Scoparioides Leaf Oil?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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