Cordyceps Extract

INCI: CORDYCEPS SINENSIS EXTRACT

CAS Number
73049-73-7
Function
Extract from Cordyceps sinensis (caterpillar fungus) mycelium. Active constituents: cordycepin (3'-deoxyadenosine, antioxidant and anti-inflammatory), beta-glucans (barrier/immunomodulatory), adenosine, and polysaccharides. Mechanisms: antioxidant via cordycepin free-radical scavenging; anti-inflammatory via inhibition of pro-inflammatory cytokine production; beta-glucan barrier support; claimed adaptogenic anti-stress activity.
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted without restriction. Patent activity (CN115444928A) indicates industry R&D investment in peptide-mushroom combinations. Adaptogenic topical claims require stronger peer-reviewed validation. Antioxidant and anti-inflammatory activity better-evidenced. MoCRA safety substantiation required.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Cordyceps sinensis extract is gaining cosmetic traction through adaptogen and mushroom beauty trends with active patent investment (CN115444928A combining cordycepin with anti-aging peptides). Cordycepin provides differentiated antioxidant and anti-inflammatory activity; antioxidant and beta-glucan barrier benefits are supportable, though adaptogenic topical claims remain under-evidenced. Unrestricted globally with good tolerability.

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Concern Level: Low

Regulatory Flags

adaptogen mushroom-extract antioxidant anti-inflammatory beta-glucan holistic-beauty patent-cited claims-substantiation-required fda_food_additive

Frequently Asked Questions

Is Cordyceps Extract safe in cosmetics?

Cordyceps sinensis extract is gaining cosmetic traction through adaptogen and mushroom beauty trends with active patent investment (CN115444928A combining cordycepin with anti-aging peptides). Cordycepin provides differentiated antioxidant and anti-inflammatory activity; antioxidant and beta-glucan barrier benefits are supportable, though adaptogenic topical claims remain under-evidenced. Unrestricted globally with good tolerability. The EU classifies Cordyceps Extract as "permitted". Safety rating: GOOD.

Is Cordyceps Extract allowed in the EU?

Cordyceps Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Cordyceps Extract do in cosmetics?

Cordyceps Extract functions as: Extract from Cordyceps sinensis (caterpillar fungus) mycelium. Active constituents: cordycepin (3'-deoxyadenosine, antioxidant and anti-inflammatory), beta-glucans (barrier/immunomodulatory), adenosine, and polysaccharides. Mechanisms: antioxidant via cordycepin free-radical scavenging; anti-inflammatory via inhibition of pro-inflammatory cytokine production; beta-glucan barrier support; claimed adaptogenic anti-stress activity.. It is classified as a Active Ingredient in our database. CAS number: 73049-73-7.

What is the Margin of Safety for Cordyceps Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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