Corynanthe Yohimbe Bark Extract

INCI: CORYNANTHE YOHIMBE BARK EXTRACT

CAS Number
85117-22-2
Function
Humectant, Skin Conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Not specifically prohibited by FDA for cosmetics, but yohimbine is flagged by the National Toxicology Program for potential carcinogenicity concerns due to structural similarity to reserpine. No CIR review completed.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

EU prohibited (Annex II #337) due to structural similarity to reserpine and carcinogenicity concerns. Cardiovascular side effects reported at systemic doses. Not safe for cosmetic use in EU markets.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Corynanthe Yohimbe Bark Extract safe in cosmetics?

EU prohibited (Annex II #337) due to structural similarity to reserpine and carcinogenicity concerns. Cardiovascular side effects reported at systemic doses. Not safe for cosmetic use in EU markets. The EU classifies Corynanthe Yohimbe Bark Extract as "prohibited". Safety rating: POOR.

Is Corynanthe Yohimbe Bark Extract allowed in the EU?

Corynanthe Yohimbe Bark Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Corynanthe Yohimbe Bark Extract do in cosmetics?

Corynanthe Yohimbe Bark Extract functions as: Humectant, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 85117-22-2.

What is the Margin of Safety for Corynanthe Yohimbe Bark Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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