Diacetone Alcohol
INCI: DIACETONE ALCOHOL
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Diacetone Alcohol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 600 mg/kg bw/day | oral | rat | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Safety Opinions
Official safety assessments from the Scientific Committee on Consumer Safety (SCCS) and Cosmetic Ingredient Review (CIR).
ailable data and concluded that Diacetone Alcohol is safe in cosmetics in the present practices of use and concentration described in this safety assessment. Keywords Cosmetic Ingredient Review, Expert Panel for Cosmetic Ingredient Safety, Safety, Cosmetics, Diacetone Alcohol Introduction This
ailable data and concluded that Diacetone Alcohol is safe in cosmetics in the present practices of use and concentration described in this safety assessment. Keywords Cosmetic Ingredient Review, Expert Panel for Cosmetic Ingredient Safety, Safety, Cosmetics, Diacetone Alcohol Introduction This
ailable data and concluded that Diacetone Alcohol is safe in cosmetics in the present practices of use and concentration described in this safety assessment. Keywords Cosmetic Ingredient Review, Expert Panel for Cosmetic Ingredient Safety, Safety, Cosmetics, Diacetone Alcohol Introduction This
ailable data and concluded that Diacetone Alcohol is safe in cosmetics in the present practices of use and concentration described in this safety assessment. Keywords Cosmetic Ingredient Review, Expert Panel for Cosmetic Ingredient Safety, Safety, Cosmetics, Diacetone Alcohol Introduction This
Expert Verdict
Primarily used in nail formulations with OSHA occupational exposure limits for inhalation settings; no significant dermal concerns at current use concentrations.
Regulatory Flags
Frequently Asked Questions
Is Diacetone Alcohol safe in cosmetics?
Primarily used in nail formulations with OSHA occupational exposure limits for inhalation settings; no significant dermal concerns at current use concentrations. The EU classifies Diacetone Alcohol as "permitted". Safety rating: EXCELLENT. 2 toxicological study endpoint(s) are available in our database. This ingredient has been reviewed by cir.
Is Diacetone Alcohol allowed in the EU?
Diacetone Alcohol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Diacetone Alcohol do in cosmetics?
Diacetone Alcohol functions as: Fragrance ingredient, solvent. It is classified as a cosmetic ingredient in our database. CAS number: 123-42-2.
What is the Margin of Safety for Diacetone Alcohol?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Diacetone Alcohol?
The NOAEL (No Observed Adverse Effect Level) for Diacetone Alcohol is 100 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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