Is DIMETHYLBENZYL CARBINOL safe in cosmetics?
DIMETHYLBENZYL CARBINOL has a safety rating of "GOOD" in our database. EU status: permitted.
Good
Cosmetic Ingredient
DIMETHYLBENZYL CARBINOL
Also known as: 2-Methyl-1-phenylpropan-2-ol, Benzeneethanol, alpha,alpha-dimethyl-, Benzeneethanol, .alpha.,.alpha.-dimethyl-, 4-06-00-03290, Benzyldimethylcarbinol (+15 more)
DIMETHYLBENZYL CARBINOL (CAS 100-86-7) is a cosmetic cosmetic ingredient functioning as Perfuming. NOAEL 500 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety, pharmaceutical, and food safety data.
View industrial chemical safety profile for CAS 100-86-7 →
Auto-generated CPSR Part A draft with source citations
Chemistry & Identifiers
IUPAC Name
2-methyl-1-phenylpropan-2-ol
InChIKey
RIWRBSMFKVOJMN-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
Not specifically regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for DIMETHYLBENZYL CARBINOL across SCCS product categories, with measured dermal absorption where available.
Sensitization AOP Dashboard
Adverse Outcome Pathway data across 5 assays (DPRA, KeratinoSens, hCLAT, LLNA, NESIL) aggregated from public sources.
NESIL
1000 µg/cm²
GHS: 1B
Human: positive
Source: HPPT: [22] RIFM (1974): RIFM report number 1779, June 6, unpublished.
HRIPT Human Patch Test Studies
5 human repeat insult patch tests aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2592 | - | - |
| HMT | - | 0 | 5184 | - | - |
| HRIPT | - | 0 | 1550 | - | - |
| HRIPT | - | 0 | 1000 | - | - |
| HMT | - | 0 | 2592 | - | - |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
10 - 100 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (6)
JECFA Number
1653
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2-BENZYL-2-PROPANOL | 2007 | No safety concern at current levels of intake when used as a flavouring agent | TRS 947-JECFA68/ | FAS 59-JECFA68/
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
BENZYL DIMETHYL CARBINOL | 2007 | No safety concern at current levels of intake when used as a flavouring agent | TRS 947-JECFA68/ | FAS 59-JECFA68/
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
alpha,alpha-DIMETHYLPHENETHANOL | 2007 | No safety concern at current levels of intake when used as a flavouring agent | TRS 947-JECFA68/ | FAS 59-JECFA68/
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2-HYDROXY-2-METHYL-1-PHENYLPROPANE | 2007 | No safety concern at current levels of intake when used as a flavouring agent | TRS 947-JECFA68/ | FAS 59-JECFA68/
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for DIMETHYLBENZYL CARBINOL.
Regulatory Flags
cosing-sourced
eu-permitted
fragrance
needs-enrichment
ifra_fragrance
fda_food_additive
Known Synonyms
2-Methyl-1-phenylpropan-2-ol
Benzeneethanol, alpha,alpha-dimethyl-
Benzeneethanol, .alpha.,.alpha.-dimethyl-
4-06-00-03290
Benzyldimethylcarbinol
2-Benzyl-2-propanol
Benzylpropyl alcohol
BRN 1855608
alpha,alpha-Dimethylbenzeneethanol
Dimethylbenzylcarbinol
alpha,alpha-Dimethylphenethanol
alpha,alpha-Dimethylphenethyl alcohol
1,1-Dimethyl-2-phenylethanol
DMBC (VAN)
EINECS 202-896-0
FEMA No. 2393
2-Hydroxy-2-methyl-1-phenylpropane
2-Methyl-1-phenyl-2-propanol
NSC 27228
Phenyl-tert-butanol
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
detected; Toys and children's products
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical and food safety data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3183743
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
ALPHA,ALPHA-DIMETHYLPHENETHYL ALCOHOL
ADI
No safety concern at current levels of intake when used as a flavouring agent mg/kg bw
Food Category
flavoring
Frequently Asked Questions
Is DIMETHYLBENZYL CARBINOL allowed in the EU?
DIMETHYLBENZYL CARBINOL EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does DIMETHYLBENZYL CARBINOL do in cosmetics?
DIMETHYLBENZYL CARBINOL functions as: Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 100-86-7.
Is DIMETHYLBENZYL CARBINOL used outside cosmetics?
DIMETHYLBENZYL CARBINOL also appears in industrial chemical safety, pharmaceutical, and food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check DIMETHYLBENZYL CARBINOL compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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