Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
6 study endpoints found for Dimethylbenzyl Carbinol (DMBC). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOAEL | 50 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 500 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| dose_tested | 50 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
| NOEL | 500 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOEL | 500 mg/kg bw/day | dermal | - | dermal | REACH |
Expert Verdict
GHS: Acute Toxicity Category 4 (oral, H302); Eye Irritant Category 2A (H319); Harmful to aquatic life with long-lasting effects (H412)
Regulatory Flags
Frequently Asked Questions
Is Dimethylbenzyl Carbinol (DMBC) safe in cosmetics?
GHS: Acute Toxicity Category 4 (oral, H302); Eye Irritant Category 2A (H319); Harmful to aquatic life with long-lasting effects (H412) The EU classifies Dimethylbenzyl Carbinol (DMBC) as "permitted". Safety rating: GOOD. 6 toxicological study endpoint(s) are available in our database.
Is Dimethylbenzyl Carbinol (DMBC) allowed in the EU?
Dimethylbenzyl Carbinol (DMBC) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Dimethylbenzyl Carbinol (DMBC) do in cosmetics?
Dimethylbenzyl Carbinol (DMBC) functions as: Fragrance ingredient with warm, herbaceous, floral/lilac character. It is classified as a cosmetic ingredient in our database. CAS number: 100-86-7.
What is the Margin of Safety for Dimethylbenzyl Carbinol (DMBC)?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Dimethylbenzyl Carbinol (DMBC)?
The NOAEL (No Observed Adverse Effect Level) for Dimethylbenzyl Carbinol (DMBC) is 500 mg/kg bw/day based on a Subchronic study via oral route in rat. A total of 6 study endpoints are available. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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