Duboisia Leichhardtii Leaf Extract
INCI: DUBOISIA LEICHHARDTII LEAF EXTRACT
Regulatory Status
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Safety Data
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Expert Verdict
Critical concern — Duboisia leichhardtii is a major commercial source of tropane alkaloids (scopolamine/hyoscine, hyoscyamine, butropine, valtropine); EFSA Compendium flags tropane alkaloids; scopolamine has well-documented transdermal absorption (basis of Rx patches); even trace amounts could produce pharmacological effects (anticholinergic); a CPSR Safety Assessor should reject this ingredient without alkaloid-free certification and quantified residual alkaloid data
Regulatory Flags
Frequently Asked Questions
Is Duboisia Leichhardtii Leaf Extract safe in cosmetics?
Critical concern — Duboisia leichhardtii is a major commercial source of tropane alkaloids (scopolamine/hyoscine, hyoscyamine, butropine, valtropine); EFSA Compendium flags tropane alkaloids; scopolamine has well-documented transdermal absorption (basis of Rx patches); even trace amounts could produce pharmacological effects (anticholinergic); a CPSR Safety Assessor should reject this ingredient without alkaloid-free certification and quantified residual alkaloid data The EU classifies Duboisia Leichhardtii Leaf Extract as "permitted". Safety rating: POOR.
Is Duboisia Leichhardtii Leaf Extract allowed in the EU?
Duboisia Leichhardtii Leaf Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Duboisia Leichhardtii Leaf Extract do in cosmetics?
Duboisia Leichhardtii Leaf Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned.
What is the Margin of Safety for Duboisia Leichhardtii Leaf Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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