Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Ethyl Phenylacetate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 200 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 60 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Oral LD50 3300 mg/kg (rat) indicates moderate acute oral toxicity in pure form; safe at typical cosmetic concentrations with flash point approximately 99 °C.
Regulatory Flags
Frequently Asked Questions
Is Ethyl Phenylacetate safe in cosmetics?
Oral LD50 3300 mg/kg (rat) indicates moderate acute oral toxicity in pure form; safe at typical cosmetic concentrations with flash point approximately 99 °C. The EU classifies Ethyl Phenylacetate as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Ethyl Phenylacetate allowed in the EU?
Ethyl Phenylacetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Phenylacetate do in cosmetics?
Ethyl Phenylacetate functions as: Fragrance / Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 101-97-3.
What is the Margin of Safety for Ethyl Phenylacetate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Ethyl Phenylacetate?
The NOAEL (No Observed Adverse Effect Level) for Ethyl Phenylacetate is 200 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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