Is Ethyl Tosylamide safe in cosmetics?
Ethyl Tosylamide has a safety rating of "POOR" in our database. EU status: prohibited. US status: permitted.
Poor
Cosmetic Ingredient
Ethyl Tosylamide
Also known as: N-Ethyl-p-toluenesulfonamide, Benzenesulfonamide, N-ethyl-4-methyl-, EINECS 201-275-1, N-Ethyl-4-methyl benzenesulfonamide, N-Ethyl-p-methylbenzenesulfonamide (+7 more)
INCI: ETHYL TOSYLAMIDE
Ethyl Tosylamide (CAS 80-39-7) is a cosmetic cosmetic ingredient functioning as Film forming, plasticiser. EU Regulation 1223/2009 status: prohibited. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 80-39-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Ethyl Tosylamide is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H335).
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Film forming, plasticiser
Safety Rating
POOR
Chemistry & Identifiers
IUPAC Name
N-ethyl-4-methylbenzenesulfonamide
InChIKey
OHPZPBNDOVQJMH-UHFFFAOYSA-N
Regulatory Status
EU EU Status
prohibited
US US Status
permitted
US Notes
No FDA restrictions; listed as permitted indirect food additive; present in some US nail polishes but declining due to EU pressure
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethyl Tosylamide.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
2 property records from structured ingredient metadata.
ecotoxicity
{"biodegradable": "partial", "biodegradation_days": "90-180", "bioaccumulative": "yes", "aquatic_toxicity_level": "moderate", "coral_reef_safe": "unknown", "marine_toxicity": "moderate toxicity", "freshwater_toxicity": "persistence concerns", "endocrine_disruptor": "suspected", "persistent_organic_pollutant": "no", "microplastic": "no", "nano_particle": "no", "hawaii_banned": "no", "eu_restricted_…
pregnancy_detail
{"pregnancy_safe": "avoid", "breastfeeding_safe": "avoid", "trimester_restriction": "all", "risk_category": "not-rated", "reason": "Antibiotic resistance concern; banned in EU", "alternative_ingredient": "7-free nail polish", "source": "EU regulation"}
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Film former
Plasticizer
Regulatory List Membership (1)
FDA Indirect Food Contact Additives
Expert Verdict
Expert safety assessment and concern-level summary for Ethyl Tosylamide.
Regulatory Flags
prohibited-eu
nail-only
sulfonamide
allergen-class-risk
annex-ii
Known Synonyms
N-Ethyl-p-toluenesulfonamide
Benzenesulfonamide, N-ethyl-4-methyl-
EINECS 201-275-1
N-Ethyl-4-methyl benzenesulfonamide
N-Ethyl-p-methylbenzenesulfonamide
N-Ethyl-p-tolylsulfonamide
NSC 68803
Santicizer 3
p-Tolueneethylsulfonamide
p-Toluenesulfonyl-N-ethylamide
N-Tosylethylamine
UNII-992S798SJB
Chemical Function
Film former
Plasticizer
Regulatory Lists
CEDI
Indirect additives food contact (10/2018)
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL1492809
Frequently Asked Questions
Is Ethyl Tosylamide allowed in the EU?
Ethyl Tosylamide EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethyl Tosylamide do in cosmetics?
Ethyl Tosylamide functions as: Film forming, plasticiser. It is classified as a cosmetic ingredient in our database. CAS number: 80-39-7.
Is Ethyl Tosylamide used outside cosmetics?
Ethyl Tosylamide also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Ethyl Tosylamide have different safety status in cosmetics vs industrial chemicals?
Ethyl Tosylamide is prohibited in EU cosmetics but has active industrial GHS classifications (H315, H319, H335).
Compliance Tools
Check Ethyl Tosylamide compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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