Is Ethylhexyl Benzoate safe in cosmetics?
Ethylhexyl Benzoate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Ethylhexyl Benzoate
Also known as: Benzoic acid, 2-ethylhexyl ester, EINECS 226-641-8, 2-Ethyl-1-hexanol benzoate, NSC 19155, UNII-R63ZWW1A13
INCI: ETHYLHEXYL BENZOATE
Ethylhexyl Benzoate (CAS 5444-75-7) is a cosmetic cosmetic ingredient functioning as Emollient, skin conditioning agent. NOAEL 300 mg/kg bw/day (cross-referenced against ToxValDB ECHA IUCLID); EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 5444-75-7 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Ethylhexyl Benzoate is classified GHS Danger (H360, H360F, H413) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Emollient, skin conditioning agent
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
2-ethylhexyl benzoate
InChIKey
UADWUILHKRXHMM-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — CIR Expert Panel concluded safe as used in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ethylhexyl Benzoate.
Calculate MoS for your specific formulation with the MoS Calculator.
Pre-Calculated Safety Assessment
Pre-calculated NOAEL → SED → MoS audit trail for Ethylhexyl Benzoate across SCCS product categories, with measured dermal absorption where available.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
No longer valid
Substance Type
SUBSTANCE
SVHC Candidate
No
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
2068
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
2-ETHYLHEXYL BENZOATE | 2010 | No safety concern at current levels of intake when used as a flavouring agent | TRS 960-JECFA 73/108 | FAS 64-JECFA 73/189
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Film former
Flavouring and nutrient
Softener and conditioner
Solvent
Surfactant (surface active agent)
Wetting agent (non-aqueous)
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Expert Verdict
Expert safety assessment and concern-level summary for Ethylhexyl Benzoate.
Regulatory Flags
potential-allergen
fda_food_additive
Known Synonyms
Benzoic acid, 2-ethylhexyl ester
EINECS 226-641-8
2-Ethyl-1-hexanol benzoate
NSC 19155
UNII-R63ZWW1A13
Chemical Function
Solvent
Softener and conditioner
Surfactant (surface active agent)
Film former
Wetting agent (non-aqueous)
Flavouring and nutrient
Regulatory Lists
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Canada; pharmaceutical
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3184685
Frequently Asked Questions
Is Ethylhexyl Benzoate allowed in the EU?
Ethylhexyl Benzoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ethylhexyl Benzoate do in cosmetics?
Ethylhexyl Benzoate functions as: Emollient, skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 5444-75-7.
Is Ethylhexyl Benzoate used outside cosmetics?
Ethylhexyl Benzoate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Ethylhexyl Benzoate have different safety status in cosmetics vs industrial chemicals?
Ethylhexyl Benzoate is classified GHS Danger (H360, H360F, H413) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Ethylhexyl Benzoate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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