Excellent Emollient NOAEL Data

Ethylhexyl Cocoate

INCI: ETHYLHEXYL COCOATE

CAS Number
92044-87-6
Function
Skin Conditioning - Emollient
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

8 study endpoints found for Ethylhexyl Cocoate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 6000 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 800 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH

Expert Verdict

Safe per CIR 2011 coconut oil derivatives assessment. Hydrolyzes to 2-ethylhexanol and coconut fatty acids, both safe metabolites. Used at 0.01-41% in cosmetics.

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Concern Level: None

Frequently Asked Questions

Is Ethylhexyl Cocoate safe in cosmetics?

Safe per CIR 2011 coconut oil derivatives assessment. Hydrolyzes to 2-ethylhexanol and coconut fatty acids, both safe metabolites. Used at 0.01-41% in cosmetics. The EU classifies Ethylhexyl Cocoate as "permitted". Safety rating: EXCELLENT. 8 toxicological study endpoint(s) are available in our database.

Is Ethylhexyl Cocoate allowed in the EU?

Ethylhexyl Cocoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ethylhexyl Cocoate do in cosmetics?

Ethylhexyl Cocoate functions as: Skin Conditioning - Emollient. It is classified as a Emollient in our database. CAS number: 92044-87-6.

What is the Margin of Safety for Ethylhexyl Cocoate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Ethylhexyl Cocoate?

The NOAEL (No Observed Adverse Effect Level) for Ethylhexyl Cocoate is 1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 8 study endpoints are available. Source: REACH.

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