Euphorbia Esula Extract

INCI: EUPHORBIA ESULA EXTRACT

CAS Number
Not formally assigned for the cosmetic extract
Function
Skin conditioning
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status restricted
US Notes Permitted by omission โ€” not specifically restricted under 21 CFR, but no CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Latex contains ingenol-3-pentene-tetradecanoate (skin irritant) and ingenol-3-dodecanoate (cocarcinogenic in mouse-skin models). Classified as toxic and invasive weed with documented tumor-promoting activity.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Euphorbia Esula Extract safe in cosmetics?

Latex contains ingenol-3-pentene-tetradecanoate (skin irritant) and ingenol-3-dodecanoate (cocarcinogenic in mouse-skin models). Classified as toxic and invasive weed with documented tumor-promoting activity. The EU classifies Euphorbia Esula Extract as "permitted". Safety rating: POOR.

Is Euphorbia Esula Extract allowed in the EU?

Euphorbia Esula Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Euphorbia Esula Extract do in cosmetics?

Euphorbia Esula Extract functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not formally assigned for the cosmetic extract.

What is the Margin of Safety for Euphorbia Esula Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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