Guaiacum Officinale Extract Acetylated-Sulfated

INCI: GUAIACUM OFFICINALE EXTRACT ACETYLATED-SULFATED

CAS Number
100298-95-1
Function
Perfuming (fragrance)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical data gap โ€” chemically modified botanical extract (acetylation + sulfation of guaiac resin); no SCCS opinion, no RIFM assessment, no published toxicology studies; Guaiacum officinale is CITES Appendix II requiring sourcing documentation; sulfation introduces potential for residual sulfuric acid and sulfate ester impurities.

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Concern Level: High

Regulatory Flags

plant-extract fragrance-component natural-origin

Frequently Asked Questions

Is Guaiacum Officinale Extract Acetylated-Sulfated safe in cosmetics?

Critical data gap โ€” chemically modified botanical extract (acetylation + sulfation of guaiac resin); no SCCS opinion, no RIFM assessment, no published toxicology studies; Guaiacum officinale is CITES Appendix II requiring sourcing documentation; sulfation introduces potential for residual sulfuric acid and sulfate ester impurities. The EU classifies Guaiacum Officinale Extract Acetylated-Sulfated as "permitted". Safety rating: POOR.

Is Guaiacum Officinale Extract Acetylated-Sulfated allowed in the EU?

Guaiacum Officinale Extract Acetylated-Sulfated EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Guaiacum Officinale Extract Acetylated-Sulfated do in cosmetics?

Guaiacum Officinale Extract Acetylated-Sulfated functions as: Perfuming (fragrance). It is classified as a cosmetic ingredient in our database. CAS number: 100298-95-1.

What is the Margin of Safety for Guaiacum Officinale Extract Acetylated-Sulfated?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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