Guaiacum Sanctum Gum Extract

INCI: GUAIACUM SANCTUM GUM EXTRACT

CAS Number
91723-39-6 (tentative — verify against CosIng)
Function
Fragrance ingredient
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — guaiac gum extract listed as FEMA 2531 / 21 CFR 172.510

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical data gap — minimal published cosmetic safety data; G. sanctum is CITES Appendix II; gum resin contains phenolic oxidizable compounds used in guaiac fecal occult blood tests; these phenolics are potential sensitizers; CAS number should be independently verified in CosIng.

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen fragrance-component

Frequently Asked Questions

Is Guaiacum Sanctum Gum Extract safe in cosmetics?

Critical data gap — minimal published cosmetic safety data; G. sanctum is CITES Appendix II; gum resin contains phenolic oxidizable compounds used in guaiac fecal occult blood tests; these phenolics are potential sensitizers; CAS number should be independently verified in CosIng. The EU classifies Guaiacum Sanctum Gum Extract as "permitted". Safety rating: POOR.

Is Guaiacum Sanctum Gum Extract allowed in the EU?

Guaiacum Sanctum Gum Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Guaiacum Sanctum Gum Extract do in cosmetics?

Guaiacum Sanctum Gum Extract functions as: Fragrance ingredient. It is classified as a cosmetic ingredient in our database. CAS number: 91723-39-6 (tentative — verify against CosIng).

What is the Margin of Safety for Guaiacum Sanctum Gum Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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