Hedeoma Pulegioides (American Pennyroyal) Herb Extract

INCI: HEDEOMA PULEGIOIDES HERB EXTRACT

CAS Number
90045-40-6 (typical for this extract)
Function
Tonic; fragrance; skin conditioning
Safety Rating
POOR

Regulatory Status

🇪🇺 EU Status prohibited
🇺🇸 US Status permitted
US Notes Permitted with caution — no explicit FDA ban for topical cosmetic use, but GRAS status for food use was revoked. Pulegone is a known hepatotoxin.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CRITICAL: Contains pulegone (hepatotoxin, nephrotoxin, neurotoxin). Pulegone metabolic pathway causes liver necrosis, seizures, and death at high doses. Known abortifacient—contraindicated in pregnancy. Not recommended for children under 12. If used, must be standardized to pulegone content and comply with EU Annex III limits. IFRA restricts pennyroyal-derived ingredients.

⚠️
Concern Level: High

Regulatory Flags

plant-extract fragrance-component

Frequently Asked Questions

Is Hedeoma Pulegioides (American Pennyroyal) Herb Extract safe in cosmetics?

CRITICAL: Contains pulegone (hepatotoxin, nephrotoxin, neurotoxin). Pulegone metabolic pathway causes liver necrosis, seizures, and death at high doses. Known abortifacient—contraindicated in pregnancy. Not recommended for children under 12. If used, must be standardized to pulegone content and comply with EU Annex III limits. IFRA restricts pennyroyal-derived ingredients. The EU classifies Hedeoma Pulegioides (American Pennyroyal) Herb Extract as "prohibited". Safety rating: POOR.

Is Hedeoma Pulegioides (American Pennyroyal) Herb Extract allowed in the EU?

Hedeoma Pulegioides (American Pennyroyal) Herb Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hedeoma Pulegioides (American Pennyroyal) Herb Extract do in cosmetics?

Hedeoma Pulegioides (American Pennyroyal) Herb Extract functions as: Tonic; fragrance; skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 90045-40-6 (typical for this extract).

What is the Margin of Safety for Hedeoma Pulegioides (American Pennyroyal) Herb Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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