Is Hexahydro-tetramethyl-methanonaphthalene (Cedrene) safe in cosmetics?
Hexahydro-tetramethyl-methanonaphthalene (Cedrene) has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Hexahydro-tetramethyl-methanonaphthalene (Cedrene)
Also known as: (-)-Cedrene, 1H-3a,7-Methanoazulene, 2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-, (3R,3aS,7S,8aS)-, 1H-3a,7-Methanoazulene, 2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-, [3R-(3α,3aβ,7β,8aα)]-, Cedr-8-ene, α-Cedrene (+11 more)
INCI: HEXAHYDRO-TETRAMETHYL-METHANONAPHTHALENE
Hexahydro-tetramethyl-methanonaphthalene (Cedrene) (CAS 469-61-4) is a cosmetic cosmetic ingredient functioning as Fragrance / Perfuming. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 469-61-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Hexahydro-tetramethyl-methanonaphthalene (Cedrene) is classified GHS Danger (H226, H304, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Fragrance / Perfuming
Safety Rating
EXCELLENT
Chemistry & Identifiers
IUPAC Name
(1S,2R,5S,7S)-2,6,6,8-tetramethyltricyclo[5.3.1.01,5]undec-8-ene
InChIKey
IRAQOCYXUMOFCW-OSFYFWSMSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no restriction under 21 CFR
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexahydro-tetramethyl-methanonaphthalene (Cedrene).
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 3240 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
Consumer Product Chemical
Expert Verdict
Expert safety assessment and concern-level summary for Hexahydro-tetramethyl-methanonaphthalene (Cedrene).
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
(-)-Cedrene
1H-3a,7-Methanoazulene, 2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-, (3R,3aS,7S,8aS)-
1H-3a,7-Methanoazulene, 2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-, [3R-(3α,3aβ,7β,8aα)]-
Cedr-8-ene
α-Cedrene
Levo-α-cedrene
[3R-(3α,3aβ,7β,8αa)]-2,3,4,7,8,8a-Hexahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulene
[3R-(3α,3aβ,7β,8aα)]-2,3,4,7,8,8a-hexahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulene
[3R-(3α,3aβ,7β,8aα)]-2,3,4,7,8,8a-Hexahydro-3,6,8,8-tetramethyl-1H-3a,7-methanoazulen
[3R-(3α,3aβ,7β,8aα)]-2,3,4,7,8,8a-hexahidro-3,6,8,8-tetrametil-1H-3a,7-metanoazuleno
3-05-00-01095
BRN 3196861
EINECS 207-418-4
Levo-alpha-cedrene
Laevo-alpha-cedrene
alpha-Cedrene
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
Cleaning products and household care - air freshener; Europe
Europe
consumer_product
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Hexahydro-tetramethyl-methanonaphthalene (Cedrene) allowed in the EU?
Hexahydro-tetramethyl-methanonaphthalene (Cedrene) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexahydro-tetramethyl-methanonaphthalene (Cedrene) do in cosmetics?
Hexahydro-tetramethyl-methanonaphthalene (Cedrene) functions as: Fragrance / Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 469-61-4.
Is Hexahydro-tetramethyl-methanonaphthalene (Cedrene) used outside cosmetics?
Hexahydro-tetramethyl-methanonaphthalene (Cedrene) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Hexahydro-tetramethyl-methanonaphthalene (Cedrene) have different safety status in cosmetics vs industrial chemicals?
Hexahydro-tetramethyl-methanonaphthalene (Cedrene) is classified GHS Danger (H226, H304, H400, H410) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Hexahydro-tetramethyl-methanonaphthalene (Cedrene) compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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