Is Hexyl Octanoate safe in cosmetics?
Hexyl Octanoate has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
EXCELLENT
Cosmetic Ingredient
Hexyl Octanoate
INCI: HEXYL OCTANOATE
Hexyl Octanoate (CAS 1117-55-1) is a cosmetic cosmetic ingredient functioning as Fragrance ingredient, emollient. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
Function
Fragrance ingredient, emollient
Editorial assessment
EXCELLENT
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
hexyl octanoate
InChIKey
PBGWNXWNCSSXCO-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — FEMA GRAS; no 21 CFR 700 restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexyl Octanoate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
175
Source: WHO/JECFA
JECFA Evaluation
HEXYL CAPRYLATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/52 | FAS 40-JECFA 49/297
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (3)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Consumer Product Chemical
Editorial summary
Preliminary editorial summary for Hexyl Octanoate — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
ifra_fragrance
fda_food_additive
jecfa_safe
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
IFRA Transparency
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
consumer_product
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3182596
Frequently Asked Questions
Is Hexyl Octanoate allowed in the EU?
Hexyl Octanoate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexyl Octanoate do in cosmetics?
Hexyl Octanoate functions as: Fragrance ingredient, emollient. It is classified as a cosmetic ingredient in our database. CAS number: 1117-55-1.
Is Hexyl Octanoate used outside cosmetics?
Hexyl Octanoate also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Hexyl Octanoate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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